Results 201 to 210 of about 1,556,426 (318)

A Novel Core-Shell Hydrogel 3D Model for Studying Macrophage Mechanosensing and Foreign Body Giant Cell Formation. [PDF]

Adv Healthc Mater
Mahanty M, Ou W, Zhu X, Bromberg JS, He X, Rahaman SO.   +5 more
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Development of tetraculture spheroids as a versatile 3D model for personalized breast cancer research. [PDF]

Sci Rep
Piwocka O, Sterzyńska K, Malińska A, Suchorska WM, Kulcenty K.   +4 more
europepmc   +1 more source

Dupinsche Cyclide (Horncyclide), Brill Serie 5, Nr. 16b, 3D-Darstellung

DUPINSCHE CYCLIDE (HORNCYCLIDE), BRILL SERIE 5, NR. 16B, 3D-DARSTELLUNG Dupinsche Cyclide (Horncyclide), Brill Serie 5, Nr. 16b, 3D-Darstellung ( -
Alpers, Ulrich, Vogel, Peter
core  

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel, Timothy P. Siejka, Cassandra Marotta, Josh J. Y. Lee, Kelly Bertram, Terence J. O'Brien, Meng Law, Lucy Vivash, Ian H. Harding   +8 more
wiley   +1 more source

The Role of Stable Anatomical Landmarks in Automated 3D Model Superimposition: A Closer Look. [PDF]

Bioengineering (Basel)
Castroflorio T, Avolese S, Sanna F, Parrini S.   +3 more
europepmc   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Multiplexed Dark FRET Biosensors: An Accessible Live-Cell Platform for Target- and Cell-Specific Monitoring of Protein-Protein Interactions in 2D and 3D Model Systems. [PDF]

ACS Sens
Braun AR, Liao EE, Vunnam N, Zafari S, Nathan Kochen N, Murray M, Sachs JN.   +6 more
europepmc   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

Improved 3D reconstruction pipeline for enhancing the quality of 3D model generation from multi-view images. [PDF]

Sci Rep
Paul T, Beniwal A, Rohil MK.
europepmc   +1 more source