Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
3D modeling and fitted sphere analysis-based biotechniques unveil novel indicators for subacromial impingement syndrome. [PDF]
Yang D +6 more
europepmc +1 more source
In Vitro 3D Modeling of Neurodegenerative Diseases. [PDF]
Louit A, Galbraith T, Berthod F.
europepmc +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
3D Modeling Study of Bubble-Driven Flow and Its Interaction with Cell Operation. [PDF]
Théberge S +6 more
europepmc +1 more source
Retracted: Application of Computer 3D Modeling Technology in Graphic Image Design. [PDF]
Intelligence And Neuroscience C.
europepmc +1 more source
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Augmented reality and 3D modeling for preoperative planning in microsurgical resection of brain arteriovenous malformations: A proof-of-concept study. [PDF]
Konovalov A +10 more
europepmc +1 more source
Fully 3D Modeling of Electrochemical Deionization. [PDF]
Nordstrand J, Zuili L, Dutta J.
europepmc +1 more source
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source

