Results 41 to 50 of about 299,387 (267)

Single‐Tooth Modeling for 3D Dental Model [PDF]

International Journal of Biomedical Imaging, 2010
An integrated single‐tooth modeling scheme is proposed for the 3D dental model acquired by optical digitizers. The cores of the modeling scheme are fusion regions extraction, single tooth shape restoration, and single tooth separation. According to the “valley” shape‐like characters of the fusion regions between two adjoining teeth, the regions of the ...
Tianran Yuan, Wenhe Liao, Ning Dai, Xiaosheng Cheng, Qing Yu   +4 more
openaire   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

3D Modeling

Content: report on the choice of the 3D representation and on the 3D mapping activities. A focus of the performance assessment will be on on accuracy, reliability, and completeness of the reconstructed 3D structure both in terms of usable result for human operators as well as usage in the robotic navigation tasks.
Sander Münster, Fabrizio Ivan Apollonio, Ina Bluemel, Federico Fallavollita, Riccardo Foschi, Marc Grellert, Marinos Ioannides, Peter Heinrich Jahn, Richard Kurdiovsky, Piotr Kuroczyński, Jan-Eric Lutteroth, Heike Messemer, Georg Schelbert   +12 more
openaire   +3 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

3D Reconstruction as an Experience of Interpretation of Archaeological Materials Dedicated to the Wooden Civil Architecture of Medieval Novgorod of the X Century

Археология евразийских степей, 2023
Archaeological materials on the house-building of medieval Novgorod are a valuable source for working out issues, concerning scientific substantiation of reconstructions of the appearance of medieval buildings.
Natalia N. Faradzheva, Dmitrii A. Salomatin, Pavel A. Sapozhnikov   +2 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

The use of biocompatible composite scaffolds in oncology

Сибирский онкологический журнал, 2022
Modern tissue engineering approaches are aimed at developing scaffolds that contribute to the development of the whole variety of intercellular interactions that imitate those in a real object.The purpose of the study was to collect and summarize the ...
O. I. Kit, A. Yu. Maksimov, I. A. Novikova, A. S. Goncharova, E. A. Lukbanova, A. O. Sitkovskaya, V. G. Volovik, S. V. Chapek   +7 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

3D Modelling and Printing Technology to Produce Patient-Specific 3D Models [PDF]

Heart, Lung and Circulation, 2019
A comprehensive knowledge of mitral valve (MV) anatomy is crucial in the assessment of MV disease. While the use of three-dimensional (3D) modelling and printing in MV assessment has undergone early clinical evaluation, the precision and usefulness of this technology requires further investigation.
Nicolette S, Birbara, James M, Otton, Nalini, Pather   +2 more
openaire   +2 more sources