Results 71 to 80 of about 299,387 (267)
Journal of Intelligent Systems, 2017 The main idea behind this work is to present three-dimensional (3D) image visualization through two-dimensional (2D) images that comprise various images. 3D image visualization is one of the essential methods for excerpting data from given pieces.
Gunasekaran Ganesan +1 more
doaj +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Automated Unsupervised 3D Tool-Path Generation Using Stacked 2D Image Processing Technique
Journal of Manufacturing and Materials Processing, 2019 Tool-path, feed-rate, and depth-of-cut of a tool determine the machining time, tool wear, power consumption, and realization costs. Before the commissioning and production, a preliminary phase of failure-mode identification and effect analysis allows for
Tadele Belay Tuli, Andrea Cesarini
doaj +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
رصد النمو العمراني والتنبؤ بتغيراته المستقبلية فى مدينة العريش باستخدام نظم المعلومات الجغرافية والاستشعار عن بعد [PDF]
Maǧallaẗ Kulliyyaẗ Al-ādāb Ǧāmiʿaẗ Būrsaʿīdيعد العمران بمدينة العريش أحد أهم الركائز، التي تبنى عليها الخطط التنموية، خاصة بالفترة الاخيرة التى تتجه فيها الدولة إلى تعمير شبه جزيرة سيناء، حيث تعد المدينة أحد أهم مدن شمال سيناء وعاصمة المحافظة ليس هذا فقط بل تمثل أكبر مدن شبه جزيرة سيناء، كما إن ...
وردة أحمد السيد محمد
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Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Journal of Modern SciencePurpose: The research presented in this paper was conducted to obtain a detailed 3D model of the urinary bladder using electrical impedance tomography, a noninvasive tomographic technique.
Daria Stefańczak +3 more
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source