Results 81 to 90 of about 22,841,869 (341)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Large-Scale Urban 3D Geological Modeling Based on Multi-Method Coupling Under Multi-Source Heterogeneous Data Conditions

open access: yesApplied Sciences
The development and utilization of urban underground space represents a crucial strategy for achieving sustainable urban development. Three-dimensional (3D) geological models provide a data foundation and technical support for research in urban planning ...
Jixiang Zhu   +2 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Interoperability of photogrammetry in 3D modeling: documentation, research and dissemination in the archaeological site of Jamila

open access: yesVirtual Archaeology Review, 2015
This paper intends to be a sample, both theoretical and practical, of a protocol for the use of photogrammetric resources when generating a three-dimensional archaeological model.
Pedro R. Moya-Maleno   +3 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

The influence of mining activities on the Church of St. Cross in Bytom-Miechowice

open access: yesReports on Geodesy and Geoinformatics, 2018
The paper presents an analysis of the influence of multiannual coal exploitation on the church situated in Bytom–Miechowice. The objects has been monitored for many years by classic measurement methods as well as by the laser scanner.
Lipecki Tomasz   +2 more
doaj   +1 more source

Analysis of the 3D prototyping in the surgical correction of congenital kyphoscoliosis

open access: yesХирургия позвоночника, 2020
Objective. To analyze the advantages of additive technologies and 3D modeling in surgery for severe congenital spinal deformities caused by mixed and non-classified developmental anomalies, including assessing the quality of transpedicular screws ...
Aleksandr A. Snetkov   +4 more
doaj   +1 more source

3D modeling with silhouettes

open access: yesACM Transactions on Graphics, 2010
We present a new sketch-based modeling approach in which models are interactively designed by drawing their 2D silhouettes from different views. The core idea of our paper is to limit the input to 2D silhouettes, removing the need to explicitly create or position 3D elements. Arbitrarily complex models can be constructed by assembling them out of parts
Rivers, Alec Rothmyer   +2 more
openaire   +3 more sources

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

Digitization and Preservation of Natural Heritage Supported by Digital Fabrication Technologies

open access: yesUniciencia
[Objective] This study aimed to implement 3D image acquisition and postprocessing tools for the natural heritage preservation of a collection of craniums from a zoology museum and a wildlife rescue center.
Luis David Badilla Oviedo   +5 more
doaj   +1 more source

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