Results 101 to 110 of about 140,547 (317)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

The registration of point cloud data from range imaging camera

open access: yesGeodesy and Cartography, 2013
The measurement and 3D modelling techniques have been evolved as parallel technological improvements. Every new technique provides an opportunity for low-cost and fast measurements.
Cihan Altuntas, Ferruh Yildiz
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Patient-specific three-dimensional printing spine model for surgical planning in AO spine type-C fracture posterior long-segment fixation

open access: yesActa Orthopaedica et Traumatologica Turcica, 2022
Anıl Murat Öztürk   +4 more
doaj   +1 more source

3D Reconstruction modelling and analysis of in situ root architecture [PDF]

open access: yes
Our results show that root biomass/volume increases with time. This trend is true irrespective of the number of images used for 3D reconstruction. The increase in root volume is approximately linear with time for plants is in the early stage of growth ...
Kumar, Pankaj   +2 more
core  

Modelling of Vehicle Powertrains with the Modelica PowerTrain Library [PDF]

open access: yes, 2007
Modern powertrains increasingly include mechatronic components. Moreover, the correlation with vehicle dynamics and comfort is significant for powertrain development. Therefore, a holistic i.e.
Bünte, Tilman   +2 more
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Application and prospects of three-dimensional modelling technology in rectal cancer surgery [PDF]

open access: yesWaike lilun yu shijian
Surgery is the mainly treatment for rectal cancer. Rectal cancer surgery currently poses specific challenges due to the complex anatomy of pelvic and narrow operating area.
CHEN Zilong, ZHAO Ren
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Virtual reality urban modelling - an overview [PDF]

open access: yes, 2006
This paper offers an overview of the increasing use of Virtual Reality (VR) technologies for the simulation of urban environments. It provides a summary of cities worldwide where three-dimensional computer modelling is being utilised to aid urban ...
Horne, Margaret   +5 more
core  

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