Results 111 to 120 of about 9,013,010 (294)

Drug Repurposing for Treating NCOR‐Related Intellectual Disability

Advanced Science, EarlyView.
An autism‐associated NCOR1 heterozygous mutation upregulates NRGs and activates NRG backward signaling in hypothalamic GABAergic neurons in mouse models, leading to Gabra2 downregulation and cognitive deficits, which can be therapeutically targeted by repurposing FDA‐approved drugs.
Yan Kong, Wenjun Zhou, Yuxiang Sun, Zihan Huang, Zhiyue Liu, Udhaya Kumar. S, Chenyan Li, Yi Lu, Chengchuang Song, Veronica C. Ciliberto, Makenna Mack, Lana E. Kim, Zhaoyong Hu, Fang Luo, Aihua Cao, Zheng Sun   +15 more
wiley   +1 more source

Easy3D-Labels: Supervising Semantic Occupancy Estimation With 3D Pseudo-Labels for Automotive Perception

IEEE Open Journal of Vehicular Technology
In perception for automated vehicles, safety is critical not only for the driver but also for other agents in the scene, particularly vulnerable road users such as pedestrians and cyclists. Previous representation methods, such as Bird's Eye View,
Seamie Hayes, Ganesh Sistu, Tim Brophy, Ciaran Eising   +3 more
doaj   +1 more source

Early‐Life Manganese Overexposure Activates Microglial Phagocytosis through the YY1/TREM2 Axis Leading to Hippocampal Synaptic Remodeling in Mice

Advanced Science, EarlyView.
Early‐life manganese exposure induces behavioral deficits and aberrant hippocampal synaptic remodeling by enhancing microglial phagocytosis in young adult male mice. Mechanistically, manganese promotes Yin Yang 1 (YY1)/triggering receptor expressed on myeloid cells 2 (TREM2) signaling through enhanced HIF1α‐mediated transcription and suppressed SMURF2 ...
Keyu Chen, Bin He, Kuan Liu, Zhuo Ma, Bin Xu   +4 more
wiley   +1 more source

OpenScan: A Benchmark for Generalized Open-Vocabulary 3D Scene Understanding [PDF]

Open-vocabulary 3D scene understanding (OV-3D) aims to localize and classify novel objects beyond the closed object classes. However, existing approaches and benchmarks primarily focus on the open vocabulary problem within the context of object classes ...
Ye, Shuquan, Pang, Qianshi, Lin, Jiaying, Zhao, Youjun, Lau, Rynson W. H.   +4 more
core   +1 more source

PaSCo: Urban 3D Panoptic Scene Completion with Uncertainty Awareness

International audienceWe propose the task of Panoptic Scene Completion (PSC) which extends the recently popular Semantic Scene Completion (SSC) task with instance-level information to produce a richer understanding of the 3D scene.
de Charette, Raoul, Dai, Angela, Cao, Anh-Quan   +2 more
core   +1 more source

Single‐Nucleus Transcriptomic Atlas of Human Vellus Hair Pilosebaceous Units Reveals Age‐Associated Remodeling

Advanced Science, EarlyView.
Human vellus pilosebaceous units (PSUs) remain uncharted. This single‐nucleus atlas reveals coordinated remodeling of the aging PSU niche: reduced bulge stem cell representation with altered regenerative programs, increased representation of a stress‐responsive channel+ epithelial state, enhanced androgen‐responsive sebaceous programs, reduced ...
Ya'nan Li, Zhuoqiong Qiu, Xiaoyu Pan, Geyang Xu, Shanshan Peng, Ronghui Zhu, Qiuyang Luo, Xiaokai Fang, Xu Yao, Wei Li   +9 more
wiley   +1 more source

IoT assisted fuzzy inference systems for intelligent 3D art design in movie animation scene design

Scientific Reports
Animation scene design is assisted by intelligent computing programs and Internet of Things (IoT) services with technological advancements. Animation scene creation, modeling, and rendering require extensive computational and conditional resources.
Zhiyuan Shao
doaj   +1 more source

Pseudo‐Haptic Feedback: Multi‐Modal Approaches to Stiffness Perception and User Experience

Advanced Science, EarlyView.
Can visual deformation substitute for physical haptic feedback? In immersive VR, deformation‐based pseudo‐haptics enables stiffness discrimination comparable to wearable force feedback, while their combination yields the highest performance and presence without increasing workload.
Mehmet Ege Cansev, Xiaodong Sun, Gionata Salvietti, Domenico Prattichizzo, Philipp Beckerle   +4 more
wiley   +1 more source

ST-3DView: Multi-Scale Contrast-Enhanced 3D Point Cloud Reconstruction of Single-View Objects From Video Scene Transition

IEEE Access
3D object tracking in monocular video relies on understanding the scene content to improve the continuity of the tracking signal. Reconstructing 3D shapes of single-view objects is essential for capturing object depth, orientation, and position within ...
Dipanita Chakraborty, Werapon Chiracharit, Kosin Chamnongthai   +2 more
doaj   +1 more source

Interpretable 3D Scene Perception, Tracking and Generation

3D scene understanding is a many-pronged problem that is fundamental to countless real-world applications. These are often deployed in safety-critical situations, meaning that both accuracy and interpretability are crucial.
Santhanam, Shruthi Iyer
core