Results 31 to 40 of about 266,971 (246)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

From Strategy to Impact: How Young People Create Social and Environmental Change Through Youth Service Programs

open access: yesYouth
Young people have a desire to meaningfully contribute to their communities and create lasting impact. While youth service programs aim to support this goal, research often emphasizes youth development over social and environmental outcomes.
Ilona Dougherty   +5 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Study of Uplink Interference in UMTS Network: ASIACELL Company, Iraq

open access: yesKurdistan Journal of Applied Research, 2020
Universal Mobile Telecommunications System (UMTS), is the third generation (3G) of mobile communication which is based on the wideband code division multiple access (W-CDMA) radio access to provide bandwidth and spectral efficiency.
Bakhtiar Ali Karim, Bzhar Rahaman Othman
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Bulanık Mantık Tabanlı – Uzaktan Erişimli Sera Otomasyonu

open access: yesDüzce Üniversitesi Bilim ve Teknoloji Dergisi, 2016
Bu çalışmada endüstriyel denetim sistemlerinde yaygın olarak kullanılan PLC (Programlanabilir Mantık Denetleyicisi) ile bir sera sistemi kontrolü gerçekleştirilmiştir.
Mustafa Ayan, Ramazan Şenol
doaj  

Harnessing Vehicle-to-Vehicle Communications for 3G Downloads on the Move

open access: yesInternational Journal of Distributed Sensor Networks, 2014
This paper studies the problem of 3G downloads in vehicles on the move. Although the 3G brings larger coverage and instant access to data transfer, it may also incur high cost. We observe that many applications of vehicular 3G users can actually tolerate
Yanmin Zhu, Qinghua Chen, Chao Chen
doaj   +1 more source

Contamination of Wheat Cultivated in Various Regions of Poland during 2017 and 2018 Agricultural Seasons with Selected Trichothecenes and Their Modified Forms

open access: yesToxins, 2019
Cross-interaction of antibodies within the immunoaffinity columns used in this study facilitated the simultaneous determination of nivalenol (NIV), deoxynivalenol (DON), their glucoside derivatives (NIV-3G, DON-3G), and 3-acetyl-deoxynivalenol (3-AcDON ...
Marcin Bryła   +4 more
doaj   +1 more source

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