Results 41 to 50 of about 607 (102)

Transcription factor YcjW controls the emergency H2S production in E. coli

open access: yesNature Communications, 2019
Hydrogen sulfide (H2S) production in Escherichia coli is controlled by the sulfurtransferase 3MST. Here, the authors describe an alternative mechanism for H2S biosynthesis via activation of the thiosulfate sulfurtransferase PspE, a process mediated by ...
Lyly Luhachack   +3 more
doaj   +1 more source

Maternal N-Acetylcysteine Therapy Prevents Hypertension in Spontaneously Hypertensive Rat Offspring: Implications of Hydrogen Sulfide-Generating Pathway and Gut Microbiota

open access: yesAntioxidants, 2020
Hypertension can come from early life. N-acetylcysteine (NAC), a hydrogen sulfide (H2S) precursor as well as an antioxidant, has antihypertensive effect.
Chien-Ning Hsu   +4 more
doaj   +1 more source

A Chemiluminescence‐Activated Photodynamic Platform to Penetrate MRSA Biofilms and Counteract H2S‐Mediated Defense

open access: yesSmall Science, Volume 6, Issue 3, March 2026.
A chemiluminescence‐activated photodynamic system is developed to eradicate methicillin‐resistant Staphylococcus aureus (MRSA) biofilms without external light or antibiotics. CO2 generated in situ disrupts biofilms and propels nanocarriers for deep penetration, while hypericin generates reactive oxygen species and suppresses H2S‐mediated defenses. This
WeiYe Ren   +9 more
wiley   +1 more source

S‐Propargyl‐Cysteine Attenuates Stroke Heterogeneity via Promoting Protective Autophagy Across Multiple Neural Cell Types: Insights From Single‐Cell Sequencing

open access: yesCNS Neuroscience &Therapeutics, Volume 31, Issue 7, July 2025.
Stroke is one of the major contributors to mortality and long‐term disability. Treatments aiming at regulating endogenous protective mechanisms to reduce neurological injury after ischemic stroke are still urgently needed. Herein, we investigated the neuroprotective potential of S‐propargyl‐cysteine (SPRC), a novel water‐soluble donor of H2S, and its ...
Xiaoming Xin   +8 more
wiley   +1 more source

H2S Protects against Cardiac Cell Hypertrophy through Regulation of Selenoproteins

open access: yesOxidative Medicine and Cellular Longevity, Volume 2019, Issue 1, 2019., 2019
Cardiac hypertrophy is defined as the enlargement of the cardiac myocytes, leading to improper nourishment and oxygen supply due to the increased functional demand. This increased stress on the cardiac system commonly leads to myocardial infarction, contributing to 85% of all cardiac‐related deaths.
Adam Greasley   +6 more
wiley   +1 more source

Circulatory response to exercise relative to oxygen uptake assessed in the follow‐up of patients with fatty acid beta‐oxidation disorders

open access: yesJournal of Inherited Metabolic Disease, Volume 48, Issue 1, January 2025.
Abstract Patients with fatty acid oxidation disorders (FAODs) experience muscle symptoms due to impaired ATP metabolism and the toxicity of accumulated mitochondrial FAO substrates or intermediates, especially during catabolic states. A major issue is the absence of specific and sensible biomarkers to evaluate metabolic equilibrium.
Apolline Imbard   +17 more
wiley   +1 more source

Biological hydropersulfides and related polysulfides – a new concept and perspective in redox biology

open access: yesFEBS Letters, Volume 592, Issue 12, Page 2140-2152, June 2018., 2018
The chemical biology of thiols (RSH, e.g., cysteine and cysteine‐containing proteins/peptides) has been a topic of extreme interest for many decades due to their reported roles in protein structure/folding, redox signaling, metal ligation, cellular protection, and enzymology. While many of the studies on thiol/sulfur biochemistry have focused on thiols,
Jon M. Fukuto   +12 more
wiley   +1 more source

A Novel and Comprehensive Wellness Assessment for Lifestyle‐Based Interventions

open access: yesObesity Science &Practice, Volume 10, Issue 6, December 2024.
The purpose of this research was to develop a comprehensive Lifestyle Wellness assessment for use in lifestyle‐based wellness interventions and programs. The exploratory factor analysis produced a five‐factor model with 13 items that explained 80.3% of the variance.
Katie M. Ellison   +7 more
wiley   +1 more source

Effectiveness of mobile health for exercise promotion on cardiorespiratory fitness after a cancer diagnosis: A systematic review and meta‐analysis

open access: yesCancer Medicine, Volume 13, Issue 17, September 2024.
Abstract Background Cancer survivors are at greater risk for cardiovascular‐related mortality. Mobile health (mHealth) is an increasingly prevalent strategy for health promotion, but whether it consistently improves cardiorespiratory outcomes after a cancer diagnosis is unknown.
Megan E. Gregory   +6 more
wiley   +1 more source

26P 3MST: A potential workhorse in H2S signaling trimmed by microRNA-548 in breast cancer

open access: yesESMO Open, 2023
A. Dawoud   +5 more
openaire   +1 more source

Home - About - Disclaimer - Privacy