The possible mechanisms of action of 4-aminoquinolines (chloroquine/hydroxychloroquine) against Sars-Cov-2 infection (COVID-19): A role for iron homeostasis? [PDF]
Pharmacol Res, 2020 Quiros Roldan E +3 more
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, 1967 The contemporary physician and his patient are riding the crest of the most dramatic expansion of medical capability in history. But the rapid proliferation of medical knowledge has not been entirely benign.
Moser, Robert H.
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In-silico combinatorial design and pharmacophore modeling of potent antimalarial 4-anilinoquinolines utilizing QSAR and computed descriptors [PDF]
, 2015 core +1 more source
[Ocular toxicity due to 4-aminoquinoline derivatives].
Arquivos brasileiros de oftalmologia, 2008 Retinal toxicity of chloroquine has been extensively studied since its first description in 1957. This drug is used on a chronic basis to treat several rheumatologic and dermatologic diseases, a there is a trend to use hydroxychloroquine rather than chloroquine. The recommended dose for hydroxychloroquine is 4 mg/kg lean body weight per day.
Enéias Bezerra, Gouveia +3 more
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Modular Three-Component Synthesis of 4-Aminoquinolines via an Imidoylative Sonogashira/Cyclization Cascade. [PDF]
J Org Chem, 2018 Collet JW +5 more
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In vitro sensitivity of Plasmodium falciparum clinical isolates to 4-aminoquinolines in Northeast Nigeria. [PDF]
Malariaworld J, 2016 Balogun ST +4 more
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New Steroidal 4-Aminoquinolines Antagonize Botulinum Neurotoxin Serotype A in Mouse Embryonic Stem Cell Derived Motor Neurons in Postintoxication Model. [PDF]
J Med Chem, 2018 Konstantinović J +11 more
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Designing novel bisquinoline antimalarials from historical 4-aminoquinolines to combat drug-resistant malaria. [PDF]
Antimicrob Agents ChemotherHandford MJ +5 more
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The development and validation of an LC-MS/MS method for the determination of a new anti-malarial compound (TK900D) in human whole blood and its application to pharmacokinetic studies in ...
Efrem T Abay +6 more
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