Results 1 to 10 of about 19,883 (275)

Application of Heteropoly Acids as Heterogeneous and Recyclable Catalysts for Friedländer Synthesis of Quinolines [PDF]

E-Journal of Chemistry, 2010
New convenient conditions for the Friedländer synthesis of quinolines are described. Quinolines were readily prepared in the presence of heteropolyacids as heterogeneous and recyclable catalysts in good yields.
Majid M. Heravi, Negar Mokhtari Haj, Bita Baghernejad, Y. SH. Beheshtia, Fatemeh F. Bamoharram   +4 more
doaj   +2 more sources

Quinoline Functionalized Schiff Base Silver (I) Complexes: Interactions with Biomolecules and In Vitro Cytotoxicity, Antioxidant and Antimicrobial Activities

Molecules, 2021
A series of fifteen silver (I) quinoline complexes Q1–Q15 have been synthesized and studied for their biological activities. Q1–Q15 were synthesized from the reactions of quinolinyl Schiff base derivatives L1–L5 (obtained by condensing 2 ...
Adesola A. Adeleke, Sizwe J. Zamisa, Md. Shahidul Islam, Kolawole Olofinsan, Veronica F. Salau, Chunderika Mocktar, Bernard Omondi   +6 more
doaj   +1 more source

Iron-catalyzed indolo[2,3-c]quinoline synthesis from nitroarenes and benzylic alcohols/aldehydes promoted by elemental sulfur

Green Synthesis and Catalysis, 2022
An iron-catalyzed strategy for the rapid synthesis of indolo[2,3-c]quinolines has been developed. This cascade reaction involving alcohol oxidation, nitro reduction, and oxidative annulation was achieved in a one-pot.
Rong Li, Shuxin Jiang, Haolin Zheng, Hanwen Lei, Zhi Huang, Shanping Chen, Guo-Jun Deng   +6 more
doaj   +1 more source

A Convenient One-Pot Preparation of 2-Methyl-3-(phenylthio- methyl)quinolines from Morita-Baylis-Hillman Adducts and Their Oxidation to the Corresponding Sulfones

Molecules, 2012
A convenient one-pot preparation of 2-methyl-3-(phenylthiomethyl)quinolines from Morita-Baylis-Hillman adducts via conjugate addition of thiols followed by reductive cyclization with Fe/AcOH was developed. The 2-methyl-3-(phenylthiomethyl)quinolines were
Ching-Fa Yao, Veerababurao Kavala, Chintakunta Ramesh, Po-Min Lei, Chun-Wei Kuo   +4 more
doaj   +1 more source

Multicomponent Synthesis of 4-Aryl-4,9-dihydro-1H-pyrazolo[3,4-b]quinolines Using L-Proline as a Catalyst—Does It Really Proceed?

Molecules, 2023
Looking for effective synthetic methods for 1H-pyrazolo[3,4-b]quinolines preparation, we came across a procedure where, in a three-component reaction catalysed by L-proline, 4-aryl-4,9-dihydro-1H-pyrazolo[3,4-b]quinolines are formed.
Andrzej Danel, Elżbieta Porębska, Kacper Markiel, Oleksii Havrysh, Mateusz Kucharek, Arkadiusz Gut, Tomasz Uchacz   +6 more
doaj   +1 more source

Controlled partial transfer hydrogenation of quinolines by cobalt-amido cooperative catalysis

Nature Communications, 2020
Controlling the partial reduction of quinolines is challenging, given the competing overreduction to tetrahydroquinolines. Here, the authors report a cobalt-amido cooperative catalyst for the selective, partial transfer hydrogenation of quinolines to 1,2-
Maofu Pang, Jia-Yi Chen, Shengjie Zhang, Rong-Zhen Liao, Chen-Ho Tung, Wenguang Wang   +5 more
doaj   +1 more source

In Silico Study of Coumarins and Quinolines Derivatives as Potent Inhibitors of SARS-CoV-2 Main Protease

Frontiers in Chemistry, 2021
The pandemic that started in Wuhan (China) in 2019 has caused a large number of deaths, and infected people around the world due to the absence of effective therapy against coronavirus 2 of the severe acute respiratory syndrome (SARS-CoV-2).
Osvaldo Yañez, Osvaldo Yañez, Osvaldo Yañez, Manuel Isaías Osorio, Manuel Isaías Osorio, Eugenio Uriarte, Eugenio Uriarte, Carlos Areche, William Tiznado, José M. Pérez-Donoso, Olimpo García-Beltrán, Fernando González-Nilo   +11 more
doaj   +1 more source

TMSBr-Promoted Cascade Cyclization of ortho-Propynol Phenyl Azides for the Synthesis of 4-Bromo Quinolines and Its Applications

Molecules, 2019
Difficult-to-access 4-bromo quinolines are constructed directly from easily prepared ortho-propynol phenyl azides using TMSBr as acid-promoter. The cascade transformation performs smoothly to generate desired products in moderate to excellent yields with
Fengyan Jin, Tao Yang, Xian-Rong Song, Jiang Bai, Ruchun Yang, Haixin Ding, Qiang Xiao   +6 more
doaj   +1 more source

Are basic and lipophilic chain groups highly required in leishmanicidal quinolines to favor the phagolysosome accumulation? [PDF]

Frontiers in Chemistry
Angel H. Romero
doaj   +2 more sources

Therapeutic Activity of a Topical Formulation Containing 8-Hydroxyquinoline for Cutaneous Leishmaniasis

Pharmaceutics, 2023
Cutaneous leishmaniasis exhibits a wide spectrum of clinical manifestations; however, only a limited number of drugs are available and include Glucantime® and amphotericin B, which induce unacceptable side effects in patients, limiting their use.
Sarah Kymberly Santos de Lima, Ítalo Novaes Cavallone, Dolores Remedios Serrano, Brayan J. Anaya, Aikaterini Lalatsa, Márcia Dalastra Laurenti, João Henrique Ghilardi Lago, Dalete Christine da Silva Souza, Gabriela Pustiglione Marinsek, Beatriz Soares Lopes, Renata de Britto Mari, Luiz Felipe Domingues Passero   +11 more
doaj   +1 more source