Results 41 to 50 of about 26,162 (241)

Visible-light-driven radical Friedländer hetero-annulation of 2-aminoaryl ketone and α-methylene carbonyl compound via organic dye fluorescein through a single-electron transfer (SET) pathway

BMC Chemistry, 2022
The discoveries recommend that the photoinduced conditions of fluorescein-determined go about as impetus for photochemically combining polysubstituted quinolines in ethanol at room temperature under air environment by means of revolutionary Friedländer ...
Farzaneh Mohamadpour
doaj   +1 more source

Diazo Transfer From Nitrous Oxide Employing Phosphorus Ylides

Angewandte Chemie, EarlyView.
A phosphorus ylide‐mediated strategy achieves the direct fixation of nitrous oxide (N2O) to access diazo compounds, which after intra‐ or intermolecular trapping, afford N2‐containing organic building blocks. This approach provides an alternative to hazardous diazo‐transfer reagents and establishes N2O fixation as a sustainable methodology.
Jhen‐Kuei Yu, Jan Niclas Ludwig, Patrick Wolf Antoni, David Tymann, Max Martin Hansmann   +4 more
wiley   +2 more sources

Catalyst-driven scaffold diversity : selective synthesis of spirocycles, carbazoles and quinolines from indolyl ynones [PDF]

, 2016
Medicinally relevant spirocyclic indolenines, carbazoles and quinolines can each be directly synthesised selectively from common indolyl ynone starting materials by catalyst variation.
Aldeghi, Burke, Cheng, Crich, Daniels, Donets, Dooley, Dorel, Galván, González-Calderón, Hamilton, Hashmi, Heffernan, Hieda, Hung, James, James, James, Kam, Karawajczyk, Knölker, Li, Liao, Lovering, López-Carrillo, Magnus, Mahatthananchai, Meiss, Modha, Mori, Nieto-Oberhuber, Nieto-Oberhuber, Peshkov, Qiu, Ramkumar, Roche, Terada, Unsworth, Wang, Wang, Wang, Wittstein, Wu, Xu, Yang, Zhang, Zhdanko, Zheng, Zhuo   +48 more
core   +1 more source

Porous Phenazine‐bridged Tetraoxa[8]Circulenes for Selective Gold Recovery and Heterogeneous Catalysis

Angewandte Chemie, EarlyView.
Gold recycling from electronic waste using porous materials is an emerging concept to reduce the environmental impact of gold mining. In this work, we report the synthesis of a highly porous phenazine‐derived tetraoxa[8]circulene polymer and its utilization in gold capture and heterogeneous catalysis.
Patrick W. Fritz, Eylül Attar, Timur Ashirov, Krzysztof Piech, Ali Coskun   +4 more
wiley   +2 more sources

Cyclometalated iridium complexes-catalyzed acceptorless dehydrogenative coupling reaction: construction of quinoline derivatives and evaluation of their antimicrobial activities

Beilstein Journal of Organic Chemistry, 2022
The acceptorless dehydrogenative coupling (ADC) reaction is an efficient method for synthesizing quinoline and its derivatives. In this paper, various substituted quinolines were synthesized from 2-aminobenzyl alcohols and aryl/heteroaryl/alkyl secondary
Hongling Shui, Yuhong Zhong, Renshi Luo, Zhanyi Zhang, Jiuzhong Huang, Ping Yang, Nianhua Luo   +6 more
doaj   +1 more source

Molecular monitoring of Plasmodium falciparum resistance to artemisinin in Tanzania. [PDF]

, 2006
Artemisinin-based combination therapies (ACTs) are recommended for use against uncomplicated malaria in areas of multi-drug resistant malaria, such as sub-Saharan Africa.
Kefas Mugittu, Blaise Genton, Hassan Mshinda, Hans Peter Beck, The East African Network for Monitoring Antimalarial Treatment (EANMAT), AO Talisuna, K Mugittu, PE Duffy, U Eckstein-Ludwig, AC Uhlemann, R Jambou, SP Kachur, C Falade, RN Price, MT Duraisingh, A Afonso   +15 more
core   +2 more sources

Strategies Toward Accessing Enantioenriched (Hetero)Benzo‐Fused 5‐ and 6‐ Membered Rings via Intermolecular Carbometalation

Angewandte Chemie, EarlyView.
The use of transition‐metal catalysts and design of chiral ligands have allowed chemists to access highly functionalized benzofused 5‐ and 6‐ membered rings in high yield and enantioselectivity. A common strategy used relies on an intermolecular carbometalation across alkynes and olefins, usually followed by a subsequent intramolecular carbometalation.
Clara Jans, Armaan Grewal, Xavier Abel‐Snape, Mark Lautens   +3 more
wiley   +2 more sources

Ionic Liquid as an Efficient Medium for the Synthesis of Quinoline Derivatives via α-Chymotrypsin-Catalyzed Friedländer Condensation

Molecules, 2017
An efficient, convenient, and eco-friendly biocatalytic approach was developed for the synthesis of quinoline derivatives via the α-chymotrypsin-catalyzed Friedländer reaction. Interestingly, α-chymotrypsin exhibited higher catalytic activity in an ionic
Zhang-Gao Le, Meng Liang, Zhong-Sheng Chen, Sui-Hong Zhang, Zong-Bo Xie   +4 more
doaj   +1 more source

Repositioning of Antiparasitic Drugs for Tumor Treatment

Frontiers in Oncology, 2021
Drug repositioning is a strategy for identifying new antitumor drugs; this strategy allows existing and approved clinical drugs to be innovatively repurposed to treat tumors. Based on the similarities between parasitic diseases and cancer, recent studies
Yan-Qi Li, Zhi Zheng, Quan-Xing Liu, Xiao Lu, Dong Zhou, Jiao Zhang, Hong Zheng, Ji-Gang Dai   +7 more
doaj   +1 more source

One‐Pot Amidation/C─H Halogenation by an Efficient Electrochemical Cascade

Angewandte Chemie, EarlyView.
A sustainable electrochemical cascade enables the one‐pot synthesis of regioselectively halogenated N‐aryl amides from readily available amines and acyl halides under mild conditions. The method merges amidation and C─H halogenation in a single operational step, delivering broad substrate scope, high selectivity, and scalability, and provides an ...
Sudipta Ponra, Ruzal Sitdikov, Hasil Aman, Alyssio Calis, Gergely Laczkó, Virgile Rouffeteau, Maxime R. Vitale, Imre Pápai, Oscar Verho   +8 more
wiley   +2 more sources