Results 31 to 40 of about 18,253 (267)

Multicomponent Synthesis of 4-Aryl-4,9-dihydro-1H-pyrazolo[3,4-b]quinolines Using L-Proline as a Catalyst—Does It Really Proceed?

Molecules, 2023
Looking for effective synthetic methods for 1H-pyrazolo[3,4-b]quinolines preparation, we came across a procedure where, in a three-component reaction catalysed by L-proline, 4-aryl-4,9-dihydro-1H-pyrazolo[3,4-b]quinolines are formed.
Andrzej Danel, Elżbieta Porębska, Kacper Markiel, Oleksii Havrysh, Mateusz Kucharek, Arkadiusz Gut, Tomasz Uchacz   +6 more
doaj   +1 more source

Ionic Liquid-Promoted Regiospecific Friedlander Annulation:  Novel Synthesis of Quinolines and Fused Polycyclic Quinolines [PDF]

, 2016
Several room-temperature ionic liquids (ILs) based on 1-butylimidazolium salts with varying anions were synthesized and evaluated for the preparation of biologically active substituted quinolines and fused polycyclic quinolines using the Friedlander ...
Sanjay S. Palimkar (2265799), Thomas Daniel (1307847), Shapi A. Siddiqui (2730070), Rajgopal. J. Lahoti (2730073), Kumar V. Srinivasan (2680570)   +4 more
core   +1 more source

Synthesis of Azuleno[2,1-b]quinolones and Quinolines via Brønsted Acid-Catalyzed Cyclization of 2-Arylaminoazulenes

Molecules, 2023
Quinolone and quinoline derivatives are frequently found as substructures in pharmaceutically active compounds. In this paper, we describe a procedure for the synthesis of azuleno[2,1-b]quinolones and quinolines from 2-arylaminoazulene derivatives, which
Taku Shoji, Mutsumi Takeuchi, Mayumi Uda, Yukino Ariga, Akari Yamazaki, Ryuta Sekiguchi, Shunji Ito   +6 more
doaj   +1 more source

One-Step Catalytic Synthesis of Alkyl-Substituted Quinolines [PDF]

, 2016
Difficult-to-access alkyl-substituted quinolines are formed directly from commercially available anilines, aldehydes, and alkynes bearing a variety of substituents.
Courtney E. Meyet (1734292), Catharine H. Larsen (1712905)   +1 more
core   +1 more source

Synthesis of SF5-containing benzisoxazoles, quinolines, and quinazolines by the Davis reaction of nitro-(pentafluorosulfanyl)benzenes

Beilstein Journal of Organic Chemistry, 2013
Meta- or para-nitro-(pentafluorosulfonyl)benzenes underwent the Davis reaction with arylacetonitriles to provide the SF5-containing benzisoxazoles. Good yields were obtained with arylacetonitriles containing the electron-neutral or electron-donor group ...
Petr Beier, Tereza Pastýříková
doaj   +1 more source

Quinolin-3-amine [PDF]

Acta Crystallographica Section E Structure Reports Online, 2012
In the crystal structur of the achiral title compound, C(9)H(8)N(2), N-H⋯N hydrogen bonds connect the mol-ecules into zigzag chains in [100]. Weak inter-molecular N-H⋯π inter-actions further consolidate the crystal packing.
Islor, Arun M., Chandrakantha, B., Shetty, Prakash, Gerber, Thomas, Hosten, Eric, Betz, Richard   +5 more
openaire   +2 more sources

Concise synthesis of fused polycyclic quinolines [PDF]

, 2001
β-(2-Aminophenyl)-α,β-ynones react with enamines of cyclic ketones by domino [2+2]cycloaddition/annelation reaction giving rise to bicyclo[4.2.0]-octane[7,8-c]-2-aryl quinolines or to c-fused quinolines.
G. Abbiati, E. Rossi, A. Arcadi, F. Marinelli   +3 more
core   +1 more source

Novel quinolines carrying pyridine, thienopyridine, isoquinoline, thiazolidine, thiazole and thiophene moieties as potential anticancer agents

Acta Pharmaceutica, 2016
As a part of ongoing studies in developing new anticancer agents, novel 1,2-dihydropyridine 4, thienopyridine 5, isoquinolines 6–20, acrylamide 21, thiazolidine 22, thiazoles 23–29 and thiophenes 33–35 bearing a biologically active quinoline nucleus were
Ghorab Mostafa M., Alsaid Mansour S., Al-Dosari Mohammed S., Ragab Fatma A., Al-Mishari Abdullah A., Almoqbil Abdulaziz N.   +5 more
doaj   +1 more source

A Hybrid of Amodiaquine and Primaquine Linked by Gold(I) Is a Multistage Antimalarial Agent Targeting Heme Detoxification and Thiol Redox Homeostasis

Pharmaceutics, 2022
Hybrid-based drugs linked through a transition metal constitute an emerging concept for Plasmodium intervention. To advance the drug design concept and enhance the therapeutic potential of this class of drugs, we developed a novel hybrid composed of ...
Caroline De Souza Pereira, Helenita Costa Quadros, Samuel Yaw Aboagye, Diana Fontinha, Sarah D’Alessandro, Margaret Elizabeth Byrne, Mathieu Gendrot, Isabelle Fonta, Joel Mosnier, Diogo Rodrigo M. Moreira, Nicoletta Basilico, David L. Williams, Miguel Prudêncio, Bruno Pradines, Maribel Navarro   +14 more
doaj   +1 more source

A New Green Approach to the Friedländer Synthesis of Quinolines [PDF]

, 2003
A new approach to the Friedländer synthesis of quinolines is described. Polysubstituted quinolines are readily prepared under milder conditions than in other existing methods through a gold(III)-catalysed sequential condensation/annulation reaction of o-
Sabrina Di Giuseppe, Antonio Arcadi, CHIARINI, MARCO, Fabio Marinelli   +3 more
core   +3 more sources