Results 31 to 40 of about 19,883 (275)

Iridium-catalyzed asymmetric transfer hydrogenation of quinolines with Hantzsch esters

open access: yes, 2007
The iridium-catalyzed enantioselective transfer hydrogenation of quinolines with Hantzsch esters was developed with up to 88%, ee using [Ir(COD)Cl](2)/(S)-SegPhos/I-2 as a catalyst.
Zeng, Wei   +3 more
core   +1 more source

Ag─S Sites Steer Furfural Electroreduction to Furfuryl Alcohol

open access: yesAngewandte Chemie, EarlyView.
A simple sulfide incorporation strategy turns silver into a highly active and selective catalyst for furfural electroreduction to furfuryl alcohol. Experiments combined with density functional theory reveal how isolated S sites promote hydrogenation while suppressing hydrofuroin coupling, enabling selective biomass upgrading.
Haibin Ma   +6 more
wiley   +2 more sources

Synthesis and Elimination Pathways of 1-Methanesulfonyl-1,2-dihydroquinoline Sulfonamides

open access: yesMolecules, 2023
A series of new Morita–Baylis–Hillman acetates were prepared and reacted with methanesulfonamide (K2CO3, DMF, 23 °C) to produce tertiary dihydroquinoline sulfonamides in high yields.
Ebenezer Ametsetor   +2 more
doaj   +1 more source

Asymmetric hydrogenation of quinolines activated by Bronsted acids

open access: yes, 2010
Enantioselective hydrogenation of quinolines and quinoxalines catalyzed by iridium/diphosphine complex with catalytic amount of Bronsted acid as activator was developed.
Wang, Duo-Sheng   +4 more
core   +1 more source

1‐Azabicyclo[1.1.0]butanes (ABBs) on the Map: Mechanistic Pathways for Catalytic Ring Opening and Functionalizations

open access: yesAngewandte Chemie, EarlyView.
Catalytic strain‐release ring opening and functionalizations of 1‐azabicyclo[1.1.0]butanes (ABBs) represent a promising strategy for accessing diverse azetidine products. These transformations proceed via polar pathways, radical pathways, and hybrid mechanisms that combine both.
James Shao‐Jiun Yang   +1 more
wiley   +2 more sources

Novel quinolines carrying pyridine, thienopyridine, isoquinoline, thiazolidine, thiazole and thiophene moieties as potential anticancer agents

open access: yesActa Pharmaceutica, 2016
As a part of ongoing studies in developing new anticancer agents, novel 1,2-dihydropyridine 4, thienopyridine 5, isoquinolines 6–20, acrylamide 21, thiazolidine 22, thiazoles 23–29 and thiophenes 33–35 bearing a biologically active quinoline nucleus were
Ghorab Mostafa M.   +5 more
doaj   +1 more source

Evolution of PIKK family kinase inhibitors: A new age cancer therapeutics

open access: yesFrontiers in Bioscience-Landmark, 2020
Phosphatidylinositol-3 kinase-related kinases (PIKKs) belong to a family of atypical serine/threonine kinases in humans. They actively participate in a diverse set of cellular functions such as meiotic, V(D)J recombination, chromosome maintenance, DNA ...
Althaf Shaik, Sivapriya Kirubakaran
doaj   +1 more source

Synthesis of linear azolo and pyrido quinolines from quinoline derivatives

open access: yes, 2008
Angular N-tricyclic systems as triazolo[ 4,5-f]quinolines, triazolo[ 4,5-h] quinolines, imidazo[ 4,5-f]quinolines, imidazo[ 4,5-h]quinolines were in the past obtained by connection of either f or h sides of the quinoline ring and both the adjacent carbon
Piras, S   +7 more
core   +1 more source

Visible-light-driven radical Friedländer hetero-annulation of 2-aminoaryl ketone and α-methylene carbonyl compound via organic dye fluorescein through a single-electron transfer (SET) pathway

open access: yesBMC Chemistry, 2022
The discoveries recommend that the photoinduced conditions of fluorescein-determined go about as impetus for photochemically combining polysubstituted quinolines in ethanol at room temperature under air environment by means of revolutionary Friedländer ...
Farzaneh Mohamadpour
doaj   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

open access: yesMolecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both   +7 more
wiley   +1 more source

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