Results 51 to 60 of about 18,253 (267)
Quinoline-2-carbonitrile [PDF]
In the title compound, C(10)H(6)N(2), the mol-ecule is almost planar, with an r.m.s. desviation of 0.014 Å. The dihedral angle between the aromatic rings is 1.28 (16)°. In the crystal, mol-ecules are stacked along the axis by way of weak aromatic π-π stacking inter-actions between the benzene and pyridine rings of adjacent mol-ecules [centroid-centroid
Wan-Sin Loh +3 more
openaire +3 more sources
Diversely substituted quinolines via rhodium-catalyzed alkyne hydroacylation [PDF]
The Rh-catalyzed hydroacylative union of aldehydes and o-alkynyl anilines leads to 2-aminophenyl enones, and onwards to substituted quinolines. The mild reaction conditions employed in this chemistry result in a process that displays broad functional ...
Sarah M. Morrow (2561290) +11 more
core +2 more sources
Sustainable Pd‐Catalyzed Aminations “on Dirty Water”
Aminations, done safely yet neat, and therefore, quickly, using low levels of Pd, in “dirty water” that must contain 30% KOH; not NaOH, and not at 5%,10%, 20%, 40%, or 50% KOH. Moreover, no base sensitivity of functional groups! Very cool. Thank you, Nature.
Erfan Oftadeh +4 more
wiley +2 more sources
An efficient, convenient, and eco-friendly biocatalytic approach was developed for the synthesis of quinoline derivatives via the α-chymotrypsin-catalyzed Friedländer reaction. Interestingly, α-chymotrypsin exhibited higher catalytic activity in an ionic
Zhang-Gao Le +4 more
doaj +1 more source
Repositioning of Antiparasitic Drugs for Tumor Treatment
Drug repositioning is a strategy for identifying new antitumor drugs; this strategy allows existing and approved clinical drugs to be innovatively repurposed to treat tumors. Based on the similarities between parasitic diseases and cancer, recent studies
Yan-Qi Li +7 more
doaj +1 more source
MANGO‐“Fruitcage”: A Conditional Photocage Utilizing a Fluorescence Light‐Up Aptamer
Fruitcaging ‐ a proof of concept study of a conditional photocage (Thiazol‐Orange) activated upon binding to the fluorescence light up aptamer (Mango). The prolongation of the excited state lifetime explains the redirection of the reactive pathway toward photocleavage and provides a sensitive spectroscopic readout.
Konstantinos Stamatakis +6 more
wiley +1 more source
Mechanochemical Single-Carbon Insertion into (Iso)quinolines
(Iso)quinolines are among the most common heterocycles in US Food and Drug Administration approved drugs, whereas benzoazepines are underrepresented in drug discovery libraries, primarily because of the lack of efficient preparation routes. Therefore, an
Chunxiu Jing +6 more
doaj +1 more source
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green +15 more
wiley +1 more source
Synthesis of Quinolines via Rh(III)-Catalyzed Oxidative Annulationof Pyridines [PDF]
Synthesis of Quinolines via Rh(III)-Catalyzed Oxidative Annulationof ...
公雪, 李兴伟, 宋国勇
core
Novel approach to isoindolo[2,1-a]quinolines [PDF]
International audienceAn N-acyliminium ion approach towards the synthesis of isoindolo [2,1-a]quinolines by an intramolecular process is ...
Decroix, Bernard, Pigeon, Pascal
core +1 more source

