Results 61 to 70 of about 18,253 (267)
Quinolines as chemotherapeutic agents for leishmaniasis [PDF]
, 2013 The development of leishmanicidal quinolines and their in vitro (promastigote and amastigote) and, where applicable, in vivo activities are reviewed. This survey provides a direct comparison of bioactivity across different species (e.g. L.
Young, David J +2 more
core +3 more sources
SYNTHESIS OF DERIVATIVES OF QUINOLINE. [PDF]
Journal of the American Chemical Society, 1904 n ...
Bartow, Edward, McCollum, Elmer V.
openaire +1 more source
Advanced Science, EarlyView.A one‐step, asymmetric reductive coupling of alkynes and oxa‐ and aza‐bicyclic olefins using a cobalt/photoredox catalytic system through desymmetrization. ABSTRACT Bicyclo[2.2.1]heptane frameworks represent a privileged structural motif prevalent in numerous natural products and bioactive molecules.
Subhankar Pradhan +5 more
wiley +1 more source
Synthesis of Camphor-Based Chiral Quinolines [PDF]
, 1995 Several chiral quinolines are prepared by the cyclization of imines derived from ...
Love, Brian E., Ren, Jianhua
core +1 more source
Molecules, 2010 The hydrogenation of 2-methylquinoline with Ir catalysts based on chiral phosphine-phosphites has been investigated. It has been observed that the reaction is very sensitive to the nature of the ligand. Optimization of the catalyst, allowed by the highly
Miguel Rubio, Antonio Pizzano
doaj +1 more source
Allosteric Inhibition of Polycomb Repressive Complex 2 by an EZH2‐Selective Small Molecule Inhibitor
Advanced Science, EarlyView.The study characterizes C36, a highly selective EZH2/PRC2 inhibitor that acts via a novel allosteric mechanism. Unlike previous inhibitors, C36 inhibits EZH2/PRC2 by disrupting the allosteric communication between EZH2 and EED in a SAM‐noncompetitive manner.
Ting Cao +11 more
wiley +1 more source
Enantioselective Synthesis of Endo-Cyclic Beta-Amino Acids with Two Contiguous Stereocenters via Hydrogenation of 3-Carbalkoxy-2-Substituted Quinolines. [PDF]
, 2013 Enantioselective Synthesis of Endo-Cyclic Beta-Amino Acids with Two Contiguous Stereocenters via Hydrogenation of 3-Carbalkoxy-2-Substituted ...
陈章培 +3 more
core
Selective Conversion of Diallylanilines and Arylimines to Quinolines [PDF]
, 2016 A variety of diallylanilines are shown to undergo cobalt−carbonyl catalyzed rearrangement to quinolines. Diallylanilines are also used as allyl transfer reagents to convert benzaldimines into quinolines.
William D. Jones (1351287) +1 more
core +1 more source
Phenanthrenequinone-Sensitized Photocatalytic Synthesis of Polysubstituted Quinolines from 2Vinylarylimines [PDF]
, 2021 Visible-light-excited 9,10-phenanthrenequinone (PQ*) was used as a photocatalyst for the synthesis of polysubstituted quinolines via the electrocyclization of 2-vinylarylimines.
Juulia Talvitie (11858136) +11 more
core +1 more source
Single‐Molecule Characterization of Bacterial Factor‐Dependent Transcription Activation by Rob
Advanced Science, EarlyView.Factor‐dependent transcription activation is crucial and involves complex interactions between transcription factors, RNA polymerase, and promoter DNA. Using single‐molecule assays, we show that Rob prebinds RNAP to facilitate promoter search and enhances DNA unwinding and promoter escape.
Yuqiong Zhang +7 more
wiley +1 more source