Results 81 to 90 of about 19,883 (275)
Gold Single‐Atom Catalysts Enable Selective Shuttle Hydrochlorination of Alkynes
Angewandte Chemie International Edition, EarlyView.Gold single‐atom catalysts on activated carbon enable heterogeneous shuttle hydrochlorination of terminal alkynes to vinyl chlorides with high chemo‐ and stereo‐selectivity thanks to cooperation between Au(I) sites and the support. The catalytic system combines broad substrate compatibility, simplified separation, and recoverability, paving the way for
Marc‐Eduard Usteri +8 more
wiley +1 more source
Evolution of the Quinoline Scaffold for the Treatment of Leishmaniasis: A Structural Perspective
PharmaceuticalsSince the beginning of the XXI century, Leishmaniasis has been integrated into the World Health Organization’s list of the 20 neglected tropical diseases, being considered a public health issue in more than 88 countries, especially in the tropics ...
Carlos F. M. Silva +3 more
doaj +1 more source
Investigating the Activity Spectrum for Ring-Substituted 8-Hydroxyquinolines
Molecules, 2010 In this study, a series of fourteen ring-substituted 8-hydroxyquinoline derivatives were prepared. The synthesis procedures are presented. The compounds were analyzed using RP-HPLC to determine lipophilicity.
Aidan Coffey +10 more
doaj +1 more source
Angewandte Chemie International Edition, EarlyView.We introduce the Aza‐Büchner–Curtius–Schlotterbeck (ABCS) reaction: A mild, catalyst‐free method for homologating aryl imines. Diverging from the traditional BCS mechanism, the diazo intermediate undergoes selective C─C insertion to form an all‐carbon quaternary center.
Simon O. Angerer +6 more
wiley +1 more source
, 2013 Enantioselective Synthesis of Endo-Cyclic Beta-Amino Acids with Two Contiguous Stereocenters via Hydrogenation of 3-Carbalkoxy-2-Substituted ...
陈章培 +3 more
core
Crystalline Quinolinate Phosphoribosyltransferase
Journal of Biological Chemistry, 1965 Abstract Quinolinate phosphoribosyltransferase catalyzes the formation of nicotinic acid mononucleotide, carbon dioxide, and inorganic pyrophosphate from quinolinic acid and 5-phosphoribosyl 1-pyrophosphate. The enzyme has a molecular weight of 165,000 and can be irreversibly dissociated into inactive protein units with a molecular weight of 54,000 ...
P M, Packman, W B, Jakoby
openaire +2 more sources
, 2003 Synthesis of triazolo[4,5-g]quinolines, imidazo[4,5-g]quinolines and pyrido[2,3-g]quinoxaline has been described. Antimycobacterial, antibacterial and antimycotic activity were also reported.
BOATTO, Gianpiero +5 more
core
Quinolines and analogs with a marked anticancer activity.
, 2015 Quinolines and analogs with a marked anticancer activity.
Katarzyna Malarz (829453) +6 more
core +1 more source
, 2020 Described herein is an organoborane-catalysed consecutive borylative reduction of quinolines and isoquinolines to furnish tetrahydro(iso)quinolines bearing a C(sp(3))-B bond beta to the nitrogen atom.
Sehoon Park +4 more
core +1 more source
Quinoline: A versatile heterocyclic
Saudi Pharmaceutical Journal, 2013 Quinoline or 1-aza-naphthalene is a weak tertiary base. Quinoline ring has been found to possess antimalarial, anti-bacterial, antifungal, anthelmintic, cardiotonic, anticonvulsant, anti-inflammatory, and analgesic activity. Quinoline not only has a wide range of biological and pharmacological activities but there are several established protocols for ...
Marella, Akranth +7 more
openaire +2 more sources