Results 81 to 90 of about 19,386 (276)

Exploring a Water–Ethyl Acetate System for the Efficient Synthesis of 4‐Aryl Quinolines

open access: yesChemistryOpen
Heterocyclic compounds, particularly aryl quinolines, are of paramount importance in pharmaceuticals, materials science, and agrochemicals owing to their diverse biological and physicochemical properties. However, traditional synthesis methods often rely
Mohammad Qandalee   +4 more
doaj   +1 more source

Evolution of the Quinoline Scaffold for the Treatment of Leishmaniasis: A Structural Perspective

open access: yesPharmaceuticals
Since the beginning of the XXI century, Leishmaniasis has been integrated into the World Health Organization’s list of the 20 neglected tropical diseases, being considered a public health issue in more than 88 countries, especially in the tropics ...
Carlos F. M. Silva   +3 more
doaj   +1 more source

Design, Synthesis, and In Vitro Evaluation of Benzofuro[3,2-c]Quinoline Derivatives as Potential Antileukemia Agents

open access: yesMolecules, 2020
Herein, we design and synthesize an array of benzofuro[3,2-c]quinolines starting from 3-(2-methoxyphenyl)quinolin-4(1H)ones via a sequential chlorination/demethylation, intramolecular cyclization pathway.
Ying Lin   +8 more
doaj   +1 more source

Enantioselective Synthesis of Endo-Cyclic Beta-Amino Acids with Two Contiguous Stereocenters via Hydrogenation of 3-Carbalkoxy-2-Substituted Quinolines.

open access: yes, 2013
Enantioselective Synthesis of Endo-Cyclic Beta-Amino Acids with Two Contiguous Stereocenters via Hydrogenation of 3-Carbalkoxy-2-Substituted ...
陈章培   +3 more
core  

A density functional study of N-15 chemical shielding tensors in quinolines

open access: yes, 2009
DFT calculations were carried out to characterize the N-15 shielding tensors in quinolines. This computational study is intended to shed light on the differences between two groups of quinolines: series A (7-chloro 4-aminoalkyls quinolines) and series B (
Behzadi, Hadi   +4 more
core   +1 more source

Synthesis, Structure, Chemical Stability, and In Vitro Cytotoxic Properties of Novel Quinoline-3-Carbaldehyde Hydrazones Bearing a 1,2,4-Triazole or Benzotriazole Moiety

open access: yesMolecules, 2018
A small library of novel quinoline-3-carbaldehyde hydrazones (Series 1), acylhydrazones (Series 2), and arylsulfonylhydrazones (Series 3) bearing either a 1,2,4-triazole or benzotriazole ring at position 2 was prepared, characterized by elemental ...
Martyna Korcz   +3 more
doaj   +1 more source

Novel approach to isoindolo[2,1-a]quinolines

open access: yes, 1998
International audienceAn N-acyliminium ion approach towards the synthesis of isoindolo [2,1-a]quinolines by an intramolecular process is ...
Decroix, Bernard, Pigeon, Pascal
core   +1 more source

Phenanthrenequinone-Sensitized Photocatalytic Synthesis of Polysubstituted Quinolines from 2Vinylarylimines

open access: yes, 2021
Visible-light-excited 9,10-phenanthrenequinone (PQ*) was used as a photocatalyst for the synthesis of polysubstituted quinolines via the electrocyclization of 2-vinylarylimines.
Juulia Talvitie (11858136)   +11 more
core   +1 more source

Crystalline Quinolinate Phosphoribosyltransferase

open access: yesJournal of Biological Chemistry, 1965
Abstract Quinolinate phosphoribosyltransferase catalyzes the formation of nicotinic acid mononucleotide, carbon dioxide, and inorganic pyrophosphate from quinolinic acid and 5-phosphoribosyl 1-pyrophosphate. The enzyme has a molecular weight of 165,000 and can be irreversibly dissociated into inactive protein units with a molecular weight of 54,000 ...
P M, Packman, W B, Jakoby
openaire   +2 more sources

An ETH‐LAD trip with unfavourable consequences: A case report

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Numerous analogues of the psychedelic and internationally controlled hallucinogen LSD have been described; however, only a limited number have been systematically investigated. This report presents the first case with an analytically confirmed ingestion of ETH‐LAD (6‐ethyl‐6‐nor‐lysergic acid diethylamide), the N‐ethyl derivative of LSD.
Johannes Nadler   +6 more
wiley   +1 more source

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