Results 91 to 100 of about 19,386 (276)
Quinoline: A versatile heterocyclic
Saudi Pharmaceutical Journal, 2013 Quinoline or 1-aza-naphthalene is a weak tertiary base. Quinoline ring has been found to possess antimalarial, anti-bacterial, antifungal, anthelmintic, cardiotonic, anticonvulsant, anti-inflammatory, and analgesic activity. Quinoline not only has a wide range of biological and pharmacological activities but there are several established protocols for ...
Marella, Akranth +7 more
openaire +2 more sources
Chemistry – A European Journal, EarlyView.Quinolin‐4‐ones were converted to chloroquinolinium salts, allowing formation of axially chiral aminoquinolinium salts via an enantioretentive SNAr reaction with a variety of amine nucleophiles. The salts have a high rotational barrier, with a racemization half‐life of ∼1000s of years.
Darren Holmes +5 more
wiley +1 more source
Metal-Free, Ionic Liquid-Mediated Synthesis of Functionalized Quinolines
, 2016 An expedient and metal-free synthetic protocol for construction of substituted quinolines has been developed from anilines and phenylacetaldehydes using imidazolium cation-based ionic liquids as the reaction medium.
Sandip B. Bharate (1575007) +2 more
core +1 more source
The synthesis of dimethoxy[1]benzothieno[2,3‐ c ]quinolines [PDF]
, 1986 A series of dimethoxy[1]benzothieno[2,3‐ c ]quinolines have been prepared by photocyclization of the appropriate N ‐phenyl‐3‐chlorobenzo[ b ]thiophene‐2‐carboxamides.
Castle, Raymond N., Pakray, Sudabeh
core +1 more source
Chemistry – A European Journal, EarlyView.Nitrooxylation—the installation of nitrate esters (–ONO2) has evolved from classical mixed‐acid protocols to catalytic and mechano‐, flow‐, photo‐, and electrochemical strategies. This review delineates ionic and radical manifolds for C–ONO2 bond formation, emphasizing mechanistic control, selected substrate scope, and selectivity.
Jayanta Dey, Dmitry Katayev
wiley +1 more source
Palladium-Catalyzed C‑2 Selective Arylation of Quinolines
, 2016 An efficient method for the Pd-catalyzed regioselective C-2 arylation of quinolines is presented. Reactions of various substituted quinolines and unactivated arenes have been conducted under mild conditions.
Yuling Wang (168167) +7 more
core +1 more source
Characterization of the Interaction of Known G‐quadruplex Ligands With a Minimal i‐Motif Structure
Chemistry – A European Journal, EarlyView.The destabilization of a minimal i‐Motif (iM) structure by TMPyP4 is driven by ligand recognition of one terminal iM structural domain. ABSTRACT Peculiar genomic regions are prone to evolve transiently from double‐helix DNA to noncanonical secondary structures in response to physiological stress.
Davide Auricchio +3 more
wiley +1 more source
Quinolines as chemotherapeutic agents for leishmaniasis
, 2013 The development of leishmanicidal quinolines and their in vitro (promastigote and amastigote) and, where applicable, in vivo activities are reviewed. This survey provides a direct comparison of bioactivity across different species (e.g. L.
Young, David J +2 more
core +2 more sources
Iridium-Catalyzed Ionic Hydrogenation of Multi-Aza Heterocycles. [PDF]
Angew Chem Int Ed EnglSaturated nitrogen‐containing heterocycles are ubiquitous in bioactive molecules and are thus attractive synthetic targets. A readily accessible cyclometalated iridium(III) complex reduces 14 different aromatic aza heterocycles to (partially)saturated multi aza‐heterocycles enlarging accessible chemical space while displaying high tolerance toward ...
Despois A, Cramer N.
europepmc +3 more sources
Selective Conversion of Diallylanilines and Arylimines to Quinolines
, 2016 A variety of diallylanilines are shown to undergo cobalt−carbonyl catalyzed rearrangement to quinolines. Diallylanilines are also used as allyl transfer reagents to convert benzaldimines into quinolines.
William D. Jones (1351287) +1 more
core +1 more source