Results 101 to 110 of about 26,162 (241)

1,7-Hydride transfer-involved dearomatization of quinolines to access C3-spiro hydroquinolines

Green Synthesis and Catalysis
1,7-Hydride transfer-involved dearomatization of quinolines toward C3-spiro hydroquinoline derivatives has been developed. This method offers a protocol to achieve the dearomatization of electron-deficient arenes via the redox-neutral hydride transfer ...
Da-Ying Shao, Bin Qiu, Zi-Kang Wang, Zhen-Yuan Liu, Jian Xiao, Xiao-De An   +5 more
doaj   +1 more source

Expedient Discovery of a Metallaphotoredox Cyanomethylation for Synthesizing α‐Aryl Nitriles

Chemistry – A European Journal, EarlyView.
A metallaphotoredox cyanomethylation reaction has been developed for the synthesis of valuable α‐aryl nitrile intermediates. The methodology was successfully applied to diverse medicinally‐relevant substrates, providing an expedient route to anti‐cancer Senexin compounds, while also removing the need for toxic cyanide reagents. The mechanism was probed
Gemma C. Cook, Blandine McKay, Craig Jamieson, Lee J. Edwards, Charlotte Harriman, Zackary S. Read, Simon T. Bate   +6 more
wiley   +1 more source

Investigating the Activity Spectrum for Ring-Substituted 8-Hydroxyquinolines

Molecules, 2010
In this study, a series of fourteen ring-substituted 8-hydroxyquinoline derivatives were prepared. The synthesis procedures are presented. The compounds were analyzed using RP-HPLC to determine lipophilicity.
Aidan Coffey, Jim O'Mahony, Marcela Vejsova, Katarina Kralova, James Carroll, Jacek E. Nycz, Matus Pesko, Josef Jampilek, Robert Musiol, Anna Mrozek, Jaroslaw Polanski   +10 more
doaj   +1 more source

Photoinduced Hydrogenative Dearomatization With Homocoupling of Quinolines to Construct Octahydro‐4,4'‐biquinolines

Chemistry – A European Journal, EarlyView.
Dearomative homocoupling of quinolines into 1,1',2,2',3,3',4,4'‐octahydro‐4,4'‐biquinoline (OHBQ) is reported. The photoexcited boron complex, in situ generated from quinoline, HB(pin), and KOtBu, enables the unprecedented homocoupling of tetrahydroquinolines that is challenging in the ground state, expanding the chemical diversity of OHBQ derivatives.
Mone Suzuki, Asuha Shimose, Yuki Nagashima   +2 more
wiley   +1 more source

Enhancement of the Plant‐Accessible Phosphate Fraction in Sewage Sludge Ashes by Na+ or K+ Addition Prior to Combustion

ChemSusChem, Volume 18, Issue 6, March 15, 2025.
The addition of Na2CO3 or K2CO3 to sewage sludge prior to combustion leads to the production of ashes containing phosphate in the form of buchwaldite‐like phases (Ca(Na/K)PO4). Compared to conventional sewage sludge mono‐ashes, such Na‐ or K‐ashes show greatly increased P‐solubilities and proved to be potent P‐fertiliser materials in greenhouse ...
Lorenz Bier‐Schorr, Viktoria Gräser, Michael Scherer‐Lorenzen, Peter Hajek, Philipp Kurz   +4 more
wiley   +1 more source

Remote Migratory Reductive Arylation of Unactivated Alkenes Enabled by Electrochemical Nickel Catalysis

ChemSusChem, Volume 18, Issue 6, March 15, 2025.
we have developed an electrochemical Ni−H catalyzed arylation coupling method of unactivated alkenes with aryl halides. The method displays broad functional group tolerance and proceeds under very mild conditions. Furthermore, aryl chlorides were also compatible substrates in this catalytic system. This conversion holds significant implications for the
Chao Xu, Ru‐Han A, Xiao‐Feng Wu
wiley   +1 more source

Mechanistic Paths for the Gold(I)‐Catalyzed Heteroannulation of Salicylic Amides With Apolar Alkynes Explored With Density Functional Theory Calculations

European Journal of Organic Chemistry, EarlyView.
A manifold of catalytic reaction paths can operate in the Au(I)‐catalyzed heteroannulation of salicylic amides and alkynes. However, a subtle initial nucleophilic advantage of N versus O and a kinetic bottleneck at an advanced stage of the mechanistic machinery seems to suffice for the reaction to run on a single path and with exquisite selectivity. We
Ioannis Stylianakis, Evaggelia Vlachou, Carlos Silva López, Antonios Kolocouris   +3 more
wiley   +1 more source

Push–Pull Ynamines and Push–Pull Ynamides: Synthesis, Structure, Reactivity, and Application

European Journal of Organic Chemistry, EarlyView.
Push–pull ynamines and push–pull ynamides, which carry an EWG and an amino or amido group as EDG, are highly interesting classes of EDG‐EWG alkynes that have been intensively studied due to their exceptional reactivity. In this review, the synthesis, structure, reactivity, and application of push–pull ynamines, push–pull ynecarbamates, push–pull ...
Hans‐Joachim Gais
wiley   +1 more source

1,1‐Disubstituted Vinylbromides: Versatile Building Blocks for the Synthesis of Nitrogen‐Containing Heterocycles

European Journal of Organic Chemistry, EarlyView.
1,1‐Disubstituted vinylbromides are key intermediates for constructing nitrogen‐containing heterocycles. This review provides an overview of the synthetic applications of 1,1‐disubstituted vinylbromides and summarizes recent developments in reaction methodologies, mechanistic insights, and the structural diversity of N‐heterocyclic compounds accessible
Anne Westermeyer, Jun Fang, Chonghuo Liu, Guillaume Lefèvre, Gérard Guillamot, Phannarath Phansavath, Virginie Ratovelomanana‐Vidal   +6 more
wiley   +1 more source

Multicomponent reaction access to complex quinolines via oxidation of the Povarov adducts

Beilstein Journal of Organic Chemistry, 2011
The tetrahydroquinolines obtained through the Povarov multicomponent reaction have been oxidized to the corresponding quinoline, giving access to a single product through a two-step sequence.
Esther Vicente-García, Rosario Ramón, Sara Preciado, Rodolfo Lavilla   +3 more
doaj   +1 more source