Results 121 to 130 of about 19,386 (276)

Harnessing Aggregation‐Induced Emission for Advanced Disease Diagnosis: Mechanisms, Strategies and Future Perspectives

Medicine Bulletin, EarlyView.
The figure was created in BioRender.com. ABSTRACT Accurate and early diagnosis remains a key challenge in modern disease management. Conventional diagnostic methods often suffer from limitations in sensitivity, spatial resolution, and practical usability.
Zizhuo Du, Li Song, Xingrui Chen, Jun Jing, Yingchen Wang, Yue Jiang, Jiahui Gao, Dan Li, Feiran Xie, Peihong Xiao, Ben Zhong Tang   +10 more
wiley   +1 more source

Using Quinolin-4-Ones as Convenient Common Precursors for a Metal-Free Total Synthesis of Both Dubamine and Graveoline Alkaloids and Diverse Structural Analogues

Molecules
The Rutaceae family is one of the most studied plant families due to the large number of alkaloids isolated from them with outstanding biological properties, among them the quinoline-based alkaloids Graveoline 1 and Dubamine 2.
Rodrigo Abonia, Lorena Cabrera, Diana Arteaga, Daniel Insuasty, Jairo Quiroga, Paola Cuervo, Henry Insuasty   +6 more
doaj   +1 more source

Ex vivo chemosusceptibility values for quinolines.

, 2012
Ex vivo chemosusceptibility values for quinolines.
Bernard Meunier (10931), Françoise Benoit-Vical (179530), Antoine Berry (179527), Fatima Bousejra-ElGarah (179521), Joel Lelièvre (179501), Xavier Iriart (179510), Patrice Njomnang Soh (179515), Marie-Laure Nicolau-Travers (179505), Benoit Witkowski (130751)   +8 more
core   +1 more source

Hydroxamic Acids as HDAC Inhibitor Drug Leads for Malaria

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a global health threat, with an estimated 282 million cases and 610,000 malaria‐associated deaths reported in 2024. Most mortality is due to infection by Plasmodium falciparum parasites, with the highest burden occurring in Sub‐Saharan Africa.
Wisam A. Dawood, Jacinta R. Macdonald, Christian Anzenhofer, Tina S. Skinner‐Adams, Robert C. Reid, Thomas Kurz, David P. Fairlie, Katherine T. Andrews   +7 more
wiley   +1 more source

2-Azidobenzaldehyde-Based [4+2] Annulation for the Synthesis of Quinoline Derivatives

Molecules
Quinoline is a privileged heterocyclic ring which can be found in many drug molecules and bioactive compounds. The development of synthetic methods for making quinoline derivatives continuously attracts the interest of organic and medicinal chemists ...
Xiaofeng Zhang, Miao Liu, Weiqi Qiu, Wei Zhang   +3 more
doaj   +1 more source

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

Medicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva, Alessandra Aiello, Tonino Alonzi, M. Alice Carvalho, Vladimir Finger, Delia Goletti, Sven Hoffner, Yousra Kherabi, Jan Korabecny, Julia Kulczyńska, Agnieszka Kyzioł, Alicia Lacoma, Filomena Martins, Zorica Nanovic, Sepideh Hosseiniporgham, Martina Hrast Rambaher, Leonardo Antonio Sechi, Daria Smalchuk, Grażyna Stochel, Lydia Tabernero, Nancy L. Tateosian, Violeta Valcheva, Anamarija Zega, Mafalda Sarraguça   +23 more
wiley   +1 more source

Synthesis and biological evaluation of triazolo[4,5-g]quinolines, imidazo[4,5-g]quinolines and pyrido[2,3-g]quinoxaline. Part II

, 2003
Synthesis of triazolo[4,5-g]quinolines, imidazo[4,5-g]quinolines and pyrido[2,3-g]quinoxaline has been described. Antimycobacterial, antibacterial and antimycotic activity were also reported.
BOATTO, Gianpiero, GIUSEPPE PAGLIETTI, PAOLO CAREDDA, MARIA GIOVANNA SETZU, CARTA, Antonio, GRAZIELLA PONI   +5 more
core  

Novel nitro‐quinoline photoinitiators for composites: exploring the effects of hydroxyl and methacrylate substituents on the photopolymerization of dimethacrylate matrices

Polymer International, EarlyView.
New quinoline derivatives proved to be efficient photoinitiators for dental resin monomers under two different light‐curing units, yielding favorable conversion, color and fluorescence results in the presence of different co‐initiators, including an eco‐friendly alternative.
Vitor Fernandes Moreno, Luiz Carlos da Silva‐Filho, Adilson Yoshio Furuse   +2 more
wiley   +1 more source

Palladium Catalyzed Annulation of o‑Iodo-Anilines with Propargyl Alcohols: Synthesis of Substituted Quinolines

A palladium catalyzed annulation of o-iodo-anilines with propargyl alcohols for the synthesis of substituted quinolines has been developed. The reaction tolerates diverse functional groups under mild conditions, providing direct access to 2,4 ...
Jin-Yan Liang (5801294), Zhi Zhang (55283), Jing-Tong Deng (15360267), Jia-Yi Feng (16707031), Jin-Bao Peng (1652266), Xue-Tao Xu (5059763)   +5 more
core   +2 more sources

Intramolecular radical additions to quinolines

, 2001
This paper is concerned with intramolecular radical additions to quinolines. Radical additions to C-2, C-3 and C-4 of a quinoline have all been shown to proceed under neutral conditions.
Sutton, B. J., Harrowven, D. C., Coulton, S.   +2 more
core   +1 more source