Results 131 to 140 of about 19,883 (275)

Regioselective, Molecular Iodine-Mediated C3 Iodination of Quinolines

, 2015
A novel and convenient method has been developed for the regioselective iodination of quinolines at their C3 position under metal-free conditions. Iodinated quinolines, which are popular building blocks in organic and medicinal chemistry, can be prepared
Kai Sun (140584), Lulu Liu (793645), Junjie Wang (172690), Jingjing Sun (543035), Mingyang Jia (1528651), Yunhe Lv (1528654), Zhenduo Li (1470412), Xin Wang (91924), Xin Liu (43569)   +8 more
core   +1 more source

From nature to nanoscale: advances, challenges, and preclinical translation of nanofiber drug delivery systems containing plant‐derived active ingredients

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Since the early 1960s, nanotechnology has been a critical area of science, allowing for the development of sophisticated nanomaterials. Nanofibers, one of the most widely used nanotechnological drug delivery systems, have emerged as a highly versatile platform within modern pharmaceutical sciences.
Heybet Kerem Polat, Yasin Turanlı, Nihat Kurt, Sefa Gözcü, Emre Tunçel, Hilal Bacanak, Eren Aytekin, Sedat Ünal   +7 more
wiley   +1 more source

Synthesis of Microbial‐Derived Octadecanoids

Lipids, EarlyView.
C18‐carbon containing dietary polyunsaturated fatty acids (e.g., linoleic acid, α‐linolenic acid, and γ‐linolenic acid) are metabolized by bacteria in the gut into oxygenated lipid mediators termed octadecanoids. To study the biological function of these compounds, we report here the chemical synthesis of multiple octadecanoids.
Johanna Revol‐Cavalier, Katarína Bankóová, Olivier Salamin, Alessandro Quaranta, Juan Du, Mats Hamberg, Craig E. Wheelock   +6 more
wiley   +1 more source

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

Medicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva, Alessandra Aiello, Tonino Alonzi, M. Alice Carvalho, Vladimir Finger, Delia Goletti, Sven Hoffner, Yousra Kherabi, Jan Korabecny, Julia Kulczyńska, Agnieszka Kyzioł, Alicia Lacoma, Filomena Martins, Zorica Nanovic, Sepideh Hosseiniporgham, Martina Hrast Rambaher, Leonardo Antonio Sechi, Daria Smalchuk, Grażyna Stochel, Lydia Tabernero, Nancy L. Tateosian, Violeta Valcheva, Anamarija Zega, Mafalda Sarraguça   +23 more
wiley   +1 more source

Novel Anionic Annelation Tactics for Construction of Fused Heteroaromatic Frameworks. 1. Synthesis of 4-Substituted Pyrazolo[4,3-c]quinolines, 9-Substituted Pyrazolo[3,4-c]quinolines, and 1,4-Dihydrochromeno[4,3-c]pyrazoles

, 2016
4-Substituted pyrazolo[4,3-c]quinolines 4a−i and 6a−b were prepared from pyrazole 3 whereas 9-substituted pyrazolo[3,4-c]quinolines 9a−d and 17 were prepared from pyrazole 13 utilizing anionic annelation techniques. 1,4-Dihydrochromeno[4,3-c]pyrazoles 7a−
Jan Pawlas (2335360), Per Olaf Huusfeldt (3026229), Palle Jakobsen (3026226), Per Vedsø (2730025), Mikael Begtrup (1796404)   +4 more
core   +1 more source

SÍNTESIS SELECTIVA DEL PRECURSOR DE COMPUESTOS BIOACTIVOS 4-METIL-2-QUINOLONA EMPLEANDO EL REACTIVO DE EATON

Avances en Ciencias e Ingeniería, 2019
In this paper the use of Eaton´s reagent for the selective synthesis of 4-methyl-2-quinolone is described, avoiding the use of mineral acids and expensive metal catalysts such as those described in the literature. This reagent is easily available and has
Gisela C. Muscia, Ayelen Luczywo, Juan P. Carnevale, Graciela Y. Buldain, Silvia E. Asís   +4 more
doaj  

Novel nitro‐quinoline photoinitiators for composites: exploring the effects of hydroxyl and methacrylate substituents on the photopolymerization of dimethacrylate matrices

Polymer International, EarlyView.
New quinoline derivatives proved to be efficient photoinitiators for dental resin monomers under two different light‐curing units, yielding favorable conversion, color and fluorescence results in the presence of different co‐initiators, including an eco‐friendly alternative.
Vitor Fernandes Moreno, Luiz Carlos da Silva‐Filho, Adilson Yoshio Furuse   +2 more
wiley   +1 more source

Ruta graveolens L. in Evidence‐Based Phytotherapy: Pharmacological Activities, Bioactive Compounds and Safety

Phytotherapy Research, EarlyView.
Graphical representation of ethnomedical uses, major bioactive compounds, pharmacological potential and toxicological risks of Ruta graveolens L. ABSTRACT Ruta graveolens L. is widely used in traditional European, Asian, African, and South American medicine for digestive, nervous, cardiovascular, respiratory, and reproductive disorders.
Tetiana Serhiienko, Victoriya Georgiyants, Liudas Ivanauskas, Olha Mykhailenko   +3 more
wiley   +1 more source

Cross‐Scale Engineering of Single‐Atom Catalysts from Local Planar Coordination to Spatial Architectures

Small, EarlyView.
This Review presents a cross‐scale framework for single‐atom catalysts, spanning in‐plane and out‐of‐plane coordination; primary coordination, secondary‐sphere interactions, through‐space microenvironments and support interfaces; individual sites and macroscopic architectures; and static design and directed dynamic reconstruction.
Dazhi Yao, Siheng Yang, Shuhao Wang, Bernt Johannessen, Cheng Tang   +4 more
wiley   +1 more source

Quinoline

Acta Crystallographica Section E Structure Reports Online, 2001
John E. Davies, Andrew D. Bond
openaire   +2 more sources