A 3-4 h oocyte retrieval-ICSI interval optimizes clinical outcomes for women over 40 years. [PDF]
Chen J, Wang Y, Fang C, Li T.
europepmc +1 more source
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican+7 more
wiley +1 more source
The timing of drain removal in parotidectomies: outcomes of removal at 4 h post-operatively and a Canadian survey of practice patterns. [PDF]
Liu AQ+3 more
europepmc +1 more source
Über das Hexahydro‐propiophenon, das Hexahydro‐benzyl‐methyl‐keton, den Cyclohexyl‐acetessigester und über ein eigenartiges Nebenprodukt C 10 H 12 O 4 bei der Herstellung des letzteren [PDF]
Carl Hell, Oscar Schaal
openalex +1 more source
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura+8 more
wiley +1 more source
Correction: The timing of drain removal in parotidectomies: outcomes of removal at 4 h post-operatively and a Canadian survey of practice patterns. [PDF]
Liu AQ+3 more
europepmc +1 more source
Zur Kenntniss der isomeren Verbindungen C6H8N4O4 aus Acetylmethylnitrolsäure [PDF]
Carl Steffens, Robert Behrend
openalex +1 more source
Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri+5 more
wiley +1 more source
Orbital Period and Outburst Luminosity of Transient Low Mass X-ray Binaries
In this paper we investigate the relation between the maximal luminosity of X-ray outburst and the orbital period in transient low mass X-ray binaries (or soft X-ray transients) observed by the Rossi X-ray Timing Explorer (RXTE) in the past decade.
Altamirano+50 more
core +1 more source