Results 211 to 220 of about 7,294,678 (325)

Creating positive parental influence in 4-H competitions: A guide for 4-H Volunteers

open access: yesEDIS, 2009
4H 8.5, a 4-page fact sheet by Deborah L. Nistler and Kate Fogarty, introduces a “4-As” framework for understanding parent motivations for participation in competitive youth programs, and suggests approaches for volunteers to use to encourage parent engagement. Includes references. Published by the UF 4-H Youth Development Program, December 2008.
Deborah L. Nistler, Kate Fogarty
openaire   +3 more sources

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine   +10 more
wiley   +1 more source

4-H Project Learning

open access: yesEDIS, 2014
A project is a planned series of learning experiences of six hours or more within a particular area of youth interest (Florida 4-H definition). The purpose of a 4-H project is to promote mastery of subject matter and to foster life skill development. This 4-page fact sheet was written by Judith Levings and published by the UF Department of 4-H Youth ...
openaire   +3 more sources

Getting Started in the 4-H Embryology Project: Tips for 4-H Agents and Teachers

open access: yesEDIS, 2015
Usually considered an enrichment project for classrooms, the 4-H Embryology Project can also be modified for club or individual use. In it, young people use an incubator to grow avian embryos (inside fertile eggs) through the hatching process. Students learn basic biology and life science while they eagerly look forward to hatching chicks.
Marcus Boston   +2 more
openaire   +3 more sources

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

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