Results 101 to 110 of about 92,995,374 (211)
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
4-H Club Projects Report, March 1936 [PDF]
This report for March 1936 provides the list of member names and projects completed in the Marydell (Leake County) 4-H Club as provided by club president, Leonard Evans.https://scholarsjunction.msstate.edu/mss-james-franklin-buchanan/1269/thumbnail ...
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DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
FEBS Letters, EarlyView.The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
Are 4-H Project Books Readable?
Journal of Extension, 1979 Author suggests a way 4-H can do a better job of designing 4-H publications for its target audience.
openaire +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
4-H 327 4-H Child Development Projects : Leaders Guide for the Preschooler and Middle Childhood Units [PDF]
, 1990 4-H 327: 4-H Child Development Projects Leader’s Guide for the Preschooler and Middle Childhood Units. This guide is designed to help plan learning experiences for 4-H’ers studying “The Preschooler” or “Middle Childhood” in the 4-H Child Development ...
Francis, Connie M.
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FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Virginia 4-H Foundation Newsletter
, 2015 The Virginia 4-H Foundation newsletter contains highlights of recent impacts and successes related to philanthropic support of Virginia 4-H. Volume 2, Issue 3 includes a message from the chair, as well as pieces on the 53rd Virginia State 4-H ...
Grove, Benjamin +2 more
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