Results 81 to 90 of about 904,135 (284)

RETREG1‐Mediated Reticulophagy is Essential for Dendritic Cell Maturation and Function in Sepsis

open access: yesAdvanced Science, EarlyView.
Reticulophagy regulator 1 (RETREG1) maintains dendritic cell (DC) maturation and function in early sepsis. Mechanistically, activating transcription factor 6 (ATF6) acts as a direct transcription factor regulating RETREG1 expression in response to sepsis‐induced endoplasmic reticulum (ER) stress.
Ren‐Qi Yao   +28 more
wiley   +1 more source

Minnesota 4-H Science of Agriculture Challenge: Infusing Agricultural Science and Engineering Concepts into 4-H Youth Development [PDF]

open access: yes, 2016
Youth involved in 4-H projects have been engaged in science-related endeavors for years. Since 2006, 4-H has invested considerable resources in the advancement of science learning. The new Minnesota 4-H Science of Agriculture Challenge program challenges
Davis, Sharon   +2 more
core   +2 more sources

Marburg Virus Glycoprotein Is a Remarkable Virulent Factor Linked to Hemorrhagic Pathology: Evidence from Multimodal Experimental Systems

open access: yesAdvanced Science, EarlyView.
By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao   +11 more
wiley   +1 more source

Family Engagement: Adventure Central's Healthy Response to a Common Program Challenge [PDF]

open access: yes, 2018
A common concern for youth service providers is effectively engaging adequate parental support. Providers cite challenges communicating parent expectations and having parents demonstrate success in fulfilling those expectations.
Arnett, Nate   +2 more
core  

An Increasing Misalignment Between Crop Distribution and Environmental Resources Under Climate Change in China

open access: yesAdvanced Science, EarlyView.
Climate change reshapes the spatial alignment between crop production and environmental resources. Using multi‐source data and a crop model, integrated climatic, water, and soil endowments for maize and wheat are quantified and compared with harvest distributions.
Zheng'e Su   +13 more
wiley   +1 more source

Parents\u27 Perceptions of Life Skill Development and Satisfaction With Utah 4-H [PDF]

open access: yes, 2021
The 4-H program is the nation’s largest youth development program with near six million members nationwide. Utah 4-H provides this program to the residents of Utah through Utah State University’s Extension Service.
Perry, Oakley G.
core   +1 more source

BLADE‐ON‐PETIOLE Genes Enable Genetic Bottleneck Mitigation Through Cross‐Species Repurposing of Floral Persistence Traits

open access: yesAdvanced Science, EarlyView.
This study shows that BLADE‐ON‐PETIOLE (BOP) proteins regulate floral abscission and senescence in tomato by interacting with TFAM1 to form transcriptional condensates controlling the ARABIDOPSIS THALIANA HOMEOBOX GENE 1 (ATH1)‐mediated abscission pathway.
Nan Xiao   +7 more
wiley   +1 more source

Mapping Genetic Regulation of Transcription to Identify Functional Variants and Genes Associated with Pancreatic Cancer Risk

open access: yesAdvanced Science, EarlyView.
Integration of a pancreatic eQTL map with a GWAS meta‐analysis identifies 82 putative functional variants and 15 genes. The association between rs11102484 and pancreatic cancer risk is observed in a total of 5699 cases and 8467 controls. The G allele of rs11102484 weakens ZNF263 binding and the silencer‐promoter interaction, thereby increasing ST7L ...
Xiaoyang Wang   +14 more
wiley   +1 more source

4-H School Enrichment: A Guide for 4-H Faculty and Staff

open access: yesEDIS, 2012
A partnership with the schools extends the 4‑H program to more youth through a unique delivery mode. Since School Enrichment may be a new experience for some Extension agents, this 8-page guide presents some strategies for developing a partnership with ...
Tracy A. Tesdall
doaj   +1 more source

Best Practices for Establishing Positive 4-H Youth Development Programming in Urban At-Risk Communities

open access: yesJournal of Extension, 2018
Urban, and primarily Latino, youths have traditionally been an underserved audience for the 4-H program due to language barriers, transportation issues, and lack of history with, knowledge of, and trust in the program. By developing strategies to assess community needs, develop community partnerships and collaborations, and address issues of trust and ...
Bovitz, Laura   +3 more
openaire   +2 more sources

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