Results 111 to 120 of about 7,822 (231)

Drug resistance in D. discoideum: isolation of 4-nitroquinoline 1-oxide resistant mutants [PDF]

open access: yes
The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf ...
Stegner, Andrew L.
core  

Mapping DNA damage‐dependent genetic interactions in yeast via party mating and barcode fusion genetics

open access: yesMolecular Systems Biology, 2018
Condition‐dependent genetic interactions can reveal functional relationships between genes that are not evident under standard culture conditions. State‐of‐the‐art yeast genetic interaction mapping, which relies on robotic manipulation of arrays of ...
J Javier Díaz‐Mejía   +20 more
doaj   +1 more source

NQO-Induced DNA-Less Cell Formation Is Associated with Chromatin Protein Degradation and Dependent on A0A1-ATPase in Sulfolobus

open access: yesFrontiers in Microbiology, 2017
To investigate DNA damage response in the model crenarchaeon Sulfolobus islandicus, four different DNA damage agents were tested for their effects on cell death of this archaeon, including UV irradiation, methyl methanesulfonate, cisplatin, and 4 ...
Wenyuan Han   +9 more
doaj   +1 more source

Xeroderma pigmentosum group A gene action as a protection factor against 4-nitroquinoline 1-oxide-induced tongue carcinogenesis [PDF]

open access: bronze, 2001
Fumio Ide   +6 more
openalex   +1 more source

A comparative study of the effects of three modes of 4-Nitroquinoline N-oxide induction of Sprague Dawley rats in animal models of oral leukoplakia

open access: yesOpen Life Sciences
Animal models are essential for advancing disease research. However, models for oral leukoplakia (OLK) remain relatively underexplored. This study sought to identify an optimal strategy for establishing a rat OLK model using 4-nitroquinoline 1-oxide ...
Jiao Mengyu   +8 more
doaj   +1 more source

Abstracts

open access: yesMolecular Oncology, Volume 19, Issue S1, Page 1-940, June 2025.
Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

Genotoxicity profile of fexinidazole—a drug candidate in clinical development for human African trypanomiasis (sleeping sickness) [PDF]

open access: yes, 2017
The parasitic disease human African trypanomiasis (HAT), also known as sleeping sickness, is a highly neglected fatal condition endemic in sub-Saharan Africa, which is poorly treated with medicines that are toxic, no longer effective or very difficult to
Bourdin Trunz, Bernadette   +2 more
core  

Protective effects of solvent fractions of Mentha spicata (L.) leaves evaluated on 4-nitroquinoline-1-oxide induced chromosome damage and apoptosis in mouse bone marrow cells

open access: yesGenetics and Molecular Biology, 2009
Spearmint leaves (Mentha spicata L.) contain high levels of antioxidants that are known to protect against both exogenous and endogenous DNA damage. In this study, the protective effects of the hexane fraction (HF), chloroform fraction (CF) and ethyl ...
Ponnan Arumugam, Arabandi Ramesh
doaj  

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