Network toxicology reveals collaborative mechanism of 4NQO and ethanol in esophageal squamous cell carcinogenesis [PDF]
Tobacco smoking and alcohol consumption are significant risk factors for esophageal squamous cell carcinoma (ESCC), with their Collaborative interaction amplifying carcinogenic risks.
Jianfeng Yuan +10 more
doaj +2 more sources
Comparison of injectable doxorubicin & its nanodrug complex chemotherapy for the treatment of 4-nitroquinoline-1-oxide induced oral squamous cell carcinoma in rats. [PDF]
Khiavi MM +8 more
europepmc +2 more sources
Dynamic changes in the gene expression profile during rat oral carcinogenesis induced by 4-nitroquinoline 1-oxide. [PDF]
Ge S +5 more
europepmc +3 more sources
4-Nitroquinoline 1-Oxide-Induced Tongue and Esophagus Carcinogenesis in Obese and Diabetic TSOD Mice. [PDF]
Tanaka T, Kawabata K, Sugie S.
europepmc +3 more sources
Alterations in keratins and associated proteins during 4- Nitroquinoline-1-oxide induced rat oral carcinogenesis. [PDF]
Kanojia D +4 more
europepmc +3 more sources
Interactions of 4-nitroquinoline 1-oxide with four deoxyribonucleotides [PDF]
The interactions of 4-nitroquinoline 1-oxide (NQO) with the four 5'-deoxyribonucleotides were probed using absorption spectra of the charge transfer bands and 1H and 13C nuclear magnetic resonance (NMR) spectra of nucleotide-NQO mixtures. Spectral data yielded equilibrium constants (K(dpG:NQO) = 16 M-1, K(dpA:NQO) = 12 M-1, K(dpT:NQO) = K(dpC:NQO) = 4 ...
S A, Winkle, I, Tinoco
openaire +2 more sources
Fusobacteria modulate oral carcinogenesis and promote cancer progression
Background: Evidence suggest periodontal bacterial infection can contribute to oral cancer initiation and progression. Aim: To investigate the effects of periodontal bacteria on oral cancer cell behavior using a cell-based system and a mouse ...
Amani M. Harrandah +4 more
doaj +1 more source
Constituents of tobacco that can cause DNA adduct formation and oxidative stress are implicated in the development of head and neck squamous cell carcinoma (HNSCC). However, there are few studies on the mechanism(s) that underlie tobacco-associated HNSCC.
Tingting Zhang +17 more
doaj +1 more source
Background and aims. The aim of the present study was to compare the inhibitory effects of two systemic doses of HESA-A on prevention of 4-NQO-induced tongue neoplasms in rats. This study evaluated weight and histopathological changes.
Masoumeh Mehdipour +6 more
doaj +1 more source

