Long-term cultivation of two diploid epithelial cell lines derived from normal rat liver cells [PDF]
, 1974 To obtain a useful rat liver cell line for in vitro carcinogenesis, two rat diploid epithelial cell lines were established from a 7-day-old male rat by the repeated colonial clone method.
Masuji, Hiroshi +2 more
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3-D neurohistology of transparent tongue in health and injury with optical clearing [PDF]
, 2013 Tongue receives extensive innervation to perform taste, sensory, and motor functions. Details of the tongue neuroanatomy and its plasticity in response to injury offer insights to investigate tongue neurophysiology and pathophysiology.
Ko-Jiunn Liu +4 more
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Detection and toxicity evaluation of pyrrolizidine alkaloids in medicinal plants Gynura bicolor and Gynura divaricata collected from different Chinese locations [PDF]
, 2017 Two edible plants in Southeast Asia, Gynura bicolor and G.divaricata, are not only known to be nutritive but also useful as medicinal herbs. Previous phytochemical investigation of Gynura species showed the presence of hepatotoxic pyrrolizidine alkaloids
Chen, Jian +7 more
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Ecotoxicological evaluation of caffeine and its derivatives from a simulated chlorination step [PDF]
, 2014 Caffeine is ubiquitous in surface and ground waters and it has been proposed as a marker of the anthropogenic pressure on the environment. Sewage treatment plants based on active sludges seem to be not very efficient in its complete removal from ...
Alfredo Parrella +9 more
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A comparison of transgenic rodent mutation and in vivo comet assay responses for 91 chemicals. [PDF]
, 2019 A database of 91 chemicals with published data from both transgenic rodent mutation (TGR) and rodent comet assays has been compiled. The objective was to compare the sensitivity of the two assays for detecting genotoxicity.
Aardema, MJ +26 more
core +3 more sources
Zhongliu Fangzhi Yanjiu, 2018 Objective To explore the influences of SLC39A5 knockout on the establishment of esophageal cancer model induced by 4-nitroquinoline 1-oxide (4-NQO) in C57BL/6 mice.
WANG Liqun +7 more
doaj +1 more source
Supramolecular study, Hirshfeld analysis and theoretical study of 6-methoxyquinoline N-oxide dihydrate [PDF]
, 2013 In the crystal structure of 6-methoxyquinoline N-oxide dihydrate, C10H9NO2 center dot 2H(2)O, (I), the presence of two-dimensional water networks is analysed.
Hernandez, Geraldine +3 more
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Generation and Application of Inducible Chimeric RNA ASTN2-PAPPAas Knockin Mouse Model
Cells, 2022 Chimeric RNAs (chiRNAs) play many previously unrecognized roles in different diseases including cancer. They can not only be used as biomarkers for diagnosis and prognosis of various diseases but also serve as potential therapeutic targets.
Yichen Luo +11 more
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Galectin-3 and beta-catenin expression in premalignant and carcinomatous lesions in tongue of mice [PDF]
, 2011 INTRODUÇÃO: A galectina-3 (GAL3) apresenta importantes papéis na biologia tumoral e recentemente foi mostrada a sua participação na via de sinalização Wnt, translocando a beta-catenina para o núcleo.
CARDOSO, Sérgio Vitorino +6 more
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Multifunctional photodynamic/photothermal nano-agents for the treatment of oral leukoplakia
Journal of Nanobiotechnology, 2022 Oral leukoplakia (OLK) has gained extensive attention because of the potential risk for malignant transformation. Photosensitizers (PSs) played an indispensable role in the photodynamic therapy (PDT) of OLK, but the poor light sensitivity greatly ...
Lin Lin +10 more
doaj +1 more source