Results 51 to 60 of about 7,822 (231)
Frontiers in Immunology, 2023 The herb Prunella vulgaris has shown significant immune-stimulatory and anti-inflammatory effects in mouse models. Here, the effects of a novel Prunella vulgaris-containing herbal mixture, PV-1, were examined in several mouse models for cancer, including
Qi Zhang +9 more
doaj +1 more source
Comparative evaluation of antimutagenic and antimitotic effects of Morchella esculenta extracts and protocatechuic acid [PDF]
, 2013 Morchella esculenta (L.) Pers. methanolic extracts, obtained from fruiting bodies growing wild in Serbia and Portugal, were screened for their antimutagenic properties and compared to protocatechuic acid, previously identified in both species. Salmonella
Davidović, Slobodan +7 more
core +2 more sources
Absence of genotoxic effects of the chalcone (E)-1-(2-hydroxyphenyl)-3-(4-methylphenyl)-prop-2-en-1-one) and its potential chemoprevention against DNA damage using in vitro and in vivo assays. [PDF]
PLoS ONE, 2017 The chalcone (E)-1-(2-hydroxyphenyl)-3-(4-methylphenyl)-prop-2-en-1-one), or 2HMC, displays antileishmanial, antimalarial, and antioxidant activities. The aim of this study was to investigate the cytotoxic, genotoxic, mutagenic, and protective effects of
Débora Cristina da Silva Lima +5 more
doaj +1 more source
Reduction in squamous cell carcinomas in mouse skin by dietary zinc supplementation. [PDF]
, 2016 Inadequate dietary Zn consumption increases susceptibility to esophageal and other cancers in humans and model organisms. Since Zn supplementation can prevent cancers in rodent squamous cell carcinoma (SCC) models, we were interested in determining if it
Druck, Teresa +9 more
core +2 more sources
Synthesis and Reaction of 3-Fluoro-4-nitroquinoline 1-Oxide
Chemical and Pharmaceutical Bulletin, 1968 3-Fluoroquinoline 1-oxide, which was prepared through the Schiemann reaction of 3-aminoquinoline, followed by N-oxygenation, was nitrated to 3-fluoro-4-nitroquinoline 1-oxide. The fluorine atom of this compound was replaced with nucleophiles such as OR- or NR2-containing compounds in neutral or alkaline media to afford 3-substituted 4-nitroquinoline 1 ...
M, Araki +3 more
openaire +3 more sources
Frontiers in Oncology, 2021 Oral carcinogenesis represents a multi-stage process which encompasses several genetic and molecular changes that promote the progression of oral potentially malignant disorders (OPMDs) to oral squamous cell carcinomas (OSCCs).
Jeffrey W. Chadwick +7 more
doaj +1 more source
The Genetic Basis of Mutation Rate Variation in Yeast. [PDF]
, 2018 Mutations are the root source of genetic variation and underlie the process of evolution. Although the rates at which mutations occur vary considerably between species, little is known about differences within species, or the genetic and molecular basis ...
Bloom, Joshua S +2 more
core +1 more source
Identification and dissection of a complex DNA repair sensitivity phenotype in Baker's yeast. [PDF]
PLoS Genetics, 2008 Complex traits typically involve the contribution of multiple gene variants. In this study, we took advantage of a high-density genotyping analysis of the BY (S288c) and RM strains of Saccharomyces cerevisiae and of 123 derived spore progeny to identify ...
Ann Demogines +3 more
doaj +1 more source
Frontiers in Oncology, 2022 Head and neck squamous cell carcinoma (HNSCC) is a common cancer of the oral cavity. Cisplatin (CDDP) is the ideal chemo-radiotherapy used for several tumor types, but resistance to the drug has become a major obstacle in treating patients with HNSCC.
Yu-Chieh Su +11 more
doaj +1 more source
Mutagenicity of 4-nitroquinoline l-oxide and three hair dye components in Sordaria brevicollis [PDF]
, 1981 Mutagenicity of 4-nitroquinoline 1-oxide and three hair dye components in Sordaria ...
Carter, L. A. +3 more
core +2 more sources