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小学校音楽科の学力に関する研究(1)─ 音符,休符,記号等の理解を中心として ─ [PDF]
In Japan, the purposes and contents of music education are ambiguous than in many developed countries such as England and Germany where GCSE and Abitur examinations are conducted respectively.In this article, we discussed on the academic ability of music
三村 真弓, 吉富 功修
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MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin+14 more
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Social returns to education in a developing country [PDF]
This paper estimates social returns to education in Turkey. Most evidence on spillovers from human capital comes mostly from developed countries, and estimates vary from country to country.
Filiztekin, Alpay
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The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita+1 more
wiley +1 more source
Roger Williams University Top 5 for Construction Management [PDF]
New ranking puts RWU among nation’s best 4-year construction management degree programs, citing “well-rounded” education, small class sizes, peer mentorship, dedicated advisers and tutorial support ...
Public Affairs, Roger Williams University
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NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi+5 more
wiley +1 more source
Children and Families Bill: amendments to be moved in grand committee [PDF]
Enabling power: Education Act 1996, s. 537A (4) (5) (6). Issued: 29.05.2013. Made: 20.05.2013. Laid: 29.05.2013. Coming into force: 28.06.2013. Effect: S.I. 2009/1563 amended.
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Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane+16 more
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Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas+15 more
wiley +1 more source
Girls' career aspirations [PDF]
"This report evaluates the extent to which careers education, guidance and other provision raise aspirations and inform the choices of courses and careers by girls and young women to support their long-term achievement.
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