Results 91 to 100 of about 8,196,263 (389)
Molecular Oncology, EarlyView.We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić +31 more
wiley +1 more source
Molecular Oncology, EarlyView.MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin +14 more
wiley +1 more source
Eilenberg swindles and higher large scale homology of products of trees
, 2016 We show that uniformly finite homology of products of $n$ trees vanishes in all degrees except degree $n$, where it is infinite dimensional. Our method is geometric and applies to several large scale homology theories, including almost equivariant ...
Diana, Francesca, Nowak, Piotr W.
core +1 more source
Persistence of translational symmetry in the BCS model with radial pair interaction [PDF]
, 2018 We consider the two-dimensional BCS functional with a radial pair interaction. We show that the translational symmetry is not broken in a certain temperature interval below the critical temperature.
Deuchert, Andreas +3 more
core +4 more sources
Molecular Oncology, EarlyView.TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam +9 more
wiley +1 more source
International Journal of Adaptive Control and Signal Processing, EarlyView., 2023 Summary In this contribution, we propose a detailed study of interpolation‐based data‐driven methods that are of relevance in the model reduction and also in the systems and control communities. The data are given by samples of the transfer function of the underlying (unknown) model, that is, we analyze frequency‐response data.
Quirin Aumann, Ion Victor Gosea
wiley +1 more source
Molecular Oncology, EarlyView.This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini +10 more
wiley +1 more source
Emerging Vistas for the Nutraceutical Withania somnifera in Inflammaging
PharmaceuticalsInflammaging, a coexistence of inflammation and aging, is a persistent, systemic, low-grade inflammation seen in the geriatric population. Various natural compounds have been greatly explored for their potential role in preventing and treating ...
Vivek Basudkar +5 more
doaj +1 more source
AIP Advances, 2011 Present work reports significantly high levels of ionization, eventually leading to Coulomb explosion of Tetramethyl silane (TMS) clusters, on interaction with laser pulses of intensity ∼109 W/cm2.
Purav M. Badani +4 more
doaj +1 more source
The 400-km Discontinuity [PDF]
Geophysical Journal International, 1970 Summary On the NTS-NE profile Julian and Anderson observed prominent late P arrivals indicative of a deep ‘discontinuity’ in the velocity, possibly at about 400 km depth. Additional readings of these phases were extracted from shot reports. The phases were present also in the records of two stations in azimuth 71° and 76°, but when records obtained ...
openaire +1 more source