Results 71 to 80 of about 7,930,796 (309)
Peter Jarvis, Universities and Corporate Universities: The Higher Education Industry in Global Society, London: Kogan Page, 2001. ISBN: 0–7494–3404‐X.
Barker, Philip +4 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
A critical analysis of the X.400 model of message handling systems [PDF]
The CCITT X.400 model of store and forward Message Handling Systems (MHS) serves as a common basis for the definition of electronic mail services and protocols both within CCITT and ISO.
Dorregeest, Evert, Sinderen, Marten van
core +3 more sources
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Silazane elastomer remains resilient at 400 deg C [PDF]
Smooth, unfoamed elastomer is unaffected by common acids, alkalies, and organic solvents.
core +1 more source
Jahn-Teller distortion in Cs4C60 studied by vibrational spectroscopy [PDF]
We have measured the infrared spectra of Cs(4)C(60) in the temperature range 220 - 450 K. Two anomalies in the low-frequency modes at 270 K and 400 K point to changes in molecular or crystal structure.
Borondics, Ferenc +4 more
core +1 more source
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Emerging Vistas for the Nutraceutical Withania somnifera in Inflammaging
Inflammaging, a coexistence of inflammation and aging, is a persistent, systemic, low-grade inflammation seen in the geriatric population. Various natural compounds have been greatly explored for their potential role in preventing and treating ...
Vivek Basudkar +5 more
doaj +1 more source

