Results 51 to 60 of about 2,718,842 (272)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Study of the Changes in Composition of Ammonium Diuranate with Progress of Precipitation, and Study of the Properties of Ammonium Diuranate and its Subsequent Products Produced from both Uranyl Nitrate and Uranyl Fluoride Solutions

Nuclear Engineering and Technology, 2017
Uranium metal used for fabrication of fuel for research reactors in India is generally produced by magnesio-thermic reduction of UF4. Performance of magnesio-thermic reaction and recovery and quality of uranium largely depends on properties of UF4.
Subhankar Manna, Raj Kumar, Santosh K. Satpati, Saswati B. Roy, Jyeshtharaj B. Joshi   +4 more
doaj   +1 more source

Patient Pathways During Acute in-Hospital Stroke Treatment: A Qualitative Multi-Method Study

International Journal of Integrated Care, 2022
Introduction: Patients experiencing acute ischemic stroke should access treatment as soon as possible to increase their chances for survival without severe disability.
Loraine Busetto, Johanna Hoffmann, Christina Stang, Hemasse Amiri, Fatih Seker, Jan Purrucker, Peter Arthur Ringleb, Simon Nagel, Martin Bendszus, Wolfgang Wick, Christoph Gumbinger   +10 more
doaj   +1 more source

400 Jahre englische Taufnamenforschung

, 2006
William CAMDEN launched the study of English Christian names 400 years ago. In the chapter \u27Christian Names.\u27 of his book Remaines of a Greater Worke(1605) he gives an account of the most important aspects of Christian names and presents two lists ...
Brendler, Silvio, Silvio Brendler
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Evaluation of anti-mullerian hormone in heifers and anestrus Murrah buffaloes

Indian Journal of Animal Sciences, 2019
An experiment was conducted to quantify the anti-mullerian hormone (AMH) concentration in heifers and anestrus Murrah buffaloes during fortnight blood collections for 3 months.
P M KEKAN, S D INGOLE, A S NAGVEKAR, S V BHARUCHA, S D KHARDE   +4 more
doaj   +1 more source

Tensile Strength & Durability Study on Self-Curing Concrete as a Partial Replacement of Cement by PEG-400

, 2020
The most widely used construction material, Concrete is famous for its famous properties, major of them are durability, compressive and tensile strength.
Sagar Jamle (8323491)
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Volumineuse adénopathie cervicale kystique métastatique d´un microcarcinome papillaire de la thyroïde

The Pan African Medical Journal, 2021
Une adénopathie cervicale métastatique kystique peut être confondue avec un kyste branchial ou un lymphangiome kystique. Elle peut être le seul signe révélateur d´un carcinome papillaire de la thyroïde.
Mehdi Hasnaoui, Sana Farhat
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source