Results 41 to 50 of about 450,476 (285)
Pharmaceutics, 2023 The calcium-dependent serine endoprotease PACE4 is evaluated as a therapeutic target for prostate cancer. The peptide Ac-[d-Leu]LLLRVK-amba inhibits PACE4 with high affinity and has shown efficacy in preclinical mice xenograft models of prostate cancer ...
Max Sauter +6 more
doaj +1 more source
Advanced Engineering Materials, EarlyView.Experiments and thermophysical simulations were conducted to investigate the electron beam powder bed fusion electron beam (PBF‐EB/M) process for the γ′‐strengthened nickel‐based superalloy Inconel 738LC. The results demonstrate the impact of process‐induced microstructural variations on high‐temperature mechanical behavior, providing a basis for ...
Jan Niklas Petenati +11 more
wiley +1 more source
BiomoleculesBackground: Dilated cardiomyopathy (DCM) involves myocardial remodeling, characterized by significant fibrosis and extracellular matrix expansion. These changes impair heart function, increasing the risk of heart failure and sudden cardiac death.
Elham Kayvanpour +7 more
doaj +1 more source
miR-410 controls adult SVZ neurogenesis by targeting neurogenic genes
Stem Cell Research, 2016 Over-expression of the early neural inducer, Noggin, in nestin positive subventricular zone (SVZ), neural stem cells (NSC) promotes proliferation and neuronal differentiation of neural progenitors and inhibits the expression of a CNS-enriched microRNA ...
Yao-chang Tsan +2 more
doaj +1 more source
Advanced Functional Materials, EarlyView.A multicomponent supramolecular hydrogel integrating cell‐adhesive and antibacterial peptides within an alginate‐cellulose nanofibril matrix is developed. Peptide co‐assembly simultaneously strengthens the hydrogel network, improves extrusion printability, and imparts cell‐adhesive and antibacterial functions, offering a versatile platform for ...
Mor Tsuriano‐Zernichov +4 more
wiley +1 more source
MicroRNA-410 suppresses migration and invasion by targeting MDM2 in gastric cancer. [PDF]
PLoS ONE, 2014 Gastric cancer is one of the most frequent malignancies in tumors in the East Asian countries. Identifying precise prognostic markers and effective therapeutic targets is important in the treatment of gastric cancer.
Jianjun Shen +6 more
doaj +1 more source
Pharmaceutics, 2021 Interferon-alpha (IFN-α) is suggested to cause pharmacokinetic drug interactions by lowering expression of drug disposition genes through affecting the activities of nuclear factor kappa B (NF-ĸB) and pregnane X receptor (PXR).
Dirk Theile +4 more
doaj +1 more source
Coordinated Architectural and Chemical Reinforcement in the Crushing Mandible of a Soldier Termite
Advanced Functional Materials, EarlyView.The crushing mandible of a soldier termite withstands substantial biting loads despite lacking mineral. Its cuticle is partitioned: convex teeth pair hardness and zinc enrichment with aligned chitin fibers for contact durability, while stiffer concave regions between teeth carry bending loads.
Andrew Tran Nguyen +16 more
wiley +1 more source
MGMT 410 International Business [PDF]
, 2000 Course syllabus for MGMT 410 International ...
Shaaban, Farouk
core +3 more sources
Stem Cell Research & Therapy, 2017 Background Human induced pluripotent stem cells (hiPSC) harbor the potential to differentiate into diverse cardiac cell types. Previous experimental efforts were primarily directed at the generation of hiPSC-derived cells with ventricular cardiomyocyte ...
Patrick A. Schweizer +12 more
doaj +1 more source