Results 21 to 30 of about 338,093 (288)

Rapid and Sensitive Quantification of Intracellular Glycyl-Sarcosine for Semi-High-Throughput Screening for Inhibitors of PEPT-1

Pharmaceutics, 2021
The peptide transporter PEPT-1 (SLC15A1) plays a major role in nutritional supply with amino acids by mediating the intestinal influx of dipeptides and tripeptides generated during food digestion.
Teresa von Linde, Gzona Bajraktari-Sylejmani, Walter E. Haefeli, Jürgen Burhenne, Johanna Weiss, Max Sauter   +5 more
doaj   +1 more source

Завод 410 ЦА [Zavod 410 TsA]

, 2010
«ЗАВО́Д 410 ЦА» – державне підприємство, що займається ремонтом авіаційної техніки. Розташ. у Києві. Засн. 1948 як авіац. ремонтна база № 410 Цивіл. повітр. флоту з метою ремонту двигуна АШ-62ІР, встановленого на літак Ан-2. Спочатку на підприємстві працювали лише 25 робітників, ... ⚠️ Цей запис містить лише бібліографічні метадані.
openaire   +2 more sources

MitraClip implantation followed by insertion of a left ventricular assist device in patients with advanced heart failure

ESC Heart Failure, 2020
Aims Mitral valve regurgitation (MR) is common in patients with advanced heart failure (HF). Percutaneous mitral valve repair (PMVR) via MitraClip (MC) has emerged as a feasible treatment strategy for these high‐risk patients.
Michael M. Kreusser, Sonja Hamed, Andreas Weber, Bastian Schmack, Martin J. Volz, Nicolas A. Geis, Leonie Grossekettler, Sven T. Pleger, Arjang Ruhparwar, Hugo A. Katus, Philip W. Raake   +10 more
doaj   +1 more source

Atrial fibrillation before heart transplantation is a risk factor for post‐transplant atrial fibrillation and mortality

ESC Heart Failure, 2021
Aims Atrial fibrillation (AF) after heart transplantation (HTX) is associated with worse clinical outcomes. The current study aimed to analyse the association between AF before HTX and AF within 30 days after HTX.
Fabrice F. Darche, Matthias Helmschrott, Ann‐Kathrin Rahm, Dierk Thomas, Patrick A. Schweizer, Tom Bruckner, Philipp Ehlermann, Michael M. Kreusser, Gregor Warnecke, Norbert Frey, Rasmus Rivinius   +10 more
doaj   +1 more source

Low-Cost CNC-Based media dispensing system for biotechnology laboratories

SLAS Technology
This report outlines the development and implementation of a Computer Numerical Control (CNC) based Automated Media Dispensing System (AMDS) in a plant biotechnology research laboratory.
Ping Wu, Matthew Moore, Peter Cieszewski, Kayla Beam, Sivamani Elumalai, Stephen B. Rigoulot   +5 more
doaj   +1 more source

Antivasospastic Effects of Hydroxyfasudil, a Rho-Kinase Inhibitor, After Subarachnoid Hemorrhage

Journal of Pharmacological Sciences, 2012
We investigated the anti-vasospastic potential of fasudil’s active metabolite, hydroxyfasudil, a Rho-kinase inhibitor, after subarachnoid hemorrhage (SAH) and also its effect on hemorheological abnormalities following cerebral ischemia.
Shin-ichi Satoh, Masakazu Takayasu, Koh Kawasaki, Ichiro Ikegaki, Asako Hitomi, Kazuo Yano, Masato Shibuya, Toshio Asano   +7 more
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Systemic Embolization and Myocardial Infarction due to Clinically Unrecognized Left Atrial Myxoma

Case Reports in Medicine, 2011
Myxomas are the most common primary tumors of the heart. We report an extraordinary severe case of left atrial myxoma, presenting with stroke, myocardial infarction, and multiple arterial embolism including aorta, splenic and renal arteries, and several ...
Britta Vogel, Dierk Thomas, Derliz Mereles, Wolfgang Rottbauer, Hugo A. Katus   +4 more
doaj   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source