Results 61 to 70 of about 2,478,339 (383)
ESC Heart Failure, 2020 Aims Mitral valve regurgitation (MR) is common in patients with advanced heart failure (HF). Percutaneous mitral valve repair (PMVR) via MitraClip (MC) has emerged as a feasible treatment strategy for these high‐risk patients.
Michael M. Kreusser +10 more
doaj +1 more source
Evaluation of PepT1 (SLC15A1) Substrate Characteristics of Therapeutic Cyclic Peptides
Pharmaceutics, 2022 The human peptide transporter hPepT1 (SLC15A1), physiologically transporting dipeptides and tripeptides generated during food digestion, also plays a role in the uptake of small bioactive peptides and peptide-like drugs.
Gzona Bajraktari-Sylejmani +5 more
doaj +1 more source
From conditioning to learning communities: Implications of fifty years of research in e‐learning interaction design [PDF]
, 2003 This paper will consider e‐learning in terms of the underlying learning processes and interactions that are stimulated, supported or favoured by new media and the contexts or communities in which it is used.
Ravenscroft, Andrew
core +3 more sources
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
miR-410 controls adult SVZ neurogenesis by targeting neurogenic genes
Stem Cell Research, 2016 Over-expression of the early neural inducer, Noggin, in nestin positive subventricular zone (SVZ), neural stem cells (NSC) promotes proliferation and neuronal differentiation of neural progenitors and inhibits the expression of a CNS-enriched microRNA ...
Yao-chang Tsan +2 more
doaj +1 more source
MicroRNA-410 suppresses migration and invasion by targeting MDM2 in gastric cancer. [PDF]
PLoS ONE, 2014 Gastric cancer is one of the most frequent malignancies in tumors in the East Asian countries. Identifying precise prognostic markers and effective therapeutic targets is important in the treatment of gastric cancer.
Jianjun Shen +6 more
doaj +1 more source
, 2004 Soft phonons and diffuse scattering in insulating La$_{2-x}$Sr$_{x}$CuO$_4$ ($x=0.05$) have been studied by the neutron scattering technique. The X-point phonon softens from high temperature towards the structural transition temperature $T_{s}=410$ K ...
Axe J. D. +18 more
core +1 more source
Frizzled receptor 6 marks rare, highly tumourigenic stem-like cells in mouse and human neuroblastomas [PDF]
, 2011 Copyright © 2011 Cantilena et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 3.0 License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and ...
Cantilena, S +6 more
core +2 more sources
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source