Results 41 to 50 of about 1,946,969 (304)
Chloroquine-Based Mitochondrial ATP Inhibitors
Molecules, 2023 Mitochondria is an important drug target for ailments ranging from neoplastic to neurodegenerative diseases and metabolic diseases. Here, we describe the synthesis of chloroquine analogs and show the results of mitochondrial ATP inhibition testing. The 2,
Zhiguo Wang +2 more
doaj +1 more source
Does organic farming face distinctive livestock welfare issues? - A conceptual analysis [PDF]
, 2001 The recent development and growth of organic livestock farming and the related development of national and international regulations has fuelled discussions among scientists and philosophers concerning the proper conceptualisation of animal welfare ...
Alrøe, Hugo Fjelsted +2 more
core
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective This analysis evaluates the effect of successful reperfusion on functional outcomes after MT, stratified by admission National Institutes of Health Stroke Scale (NIHSS) and Alberta Stroke Program Early CT Score (ASPECTS) as surrogates for clinical‐core mismatch, using multicenter registry data.
Felix Schlicht +53 more
wiley +1 more source
, 2011 Dans JCS 63 (2011) 65-72, A. Löhnert a publié un nouveau duplicat de "La lamentation sur Ur" (BM 79966), lequel montre qu'à la I. 430, la meilleure lecon n'est peut-être pas lu2 (CC), mais diĝir (P et BM 79966): diĝir a-ra-zu im-me-a-bi(-ir3) ša3 ḫa-ba(-an)-na-ḫuĝ-e "Puisse (ton [de Nanna]) coeur s'apaiser face à ce dieu qui (t')adresse des prières ...
openaire +2 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon +11 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou +15 more
wiley +1 more source
Review of energy management guidance for water and wastewater utilities
Energy Nexus, 2023 Water and wastewater utilities consume significant energy, and much guidance has emerged especially in the past 25 years to help them manage it. The confluence of literature from independent groups in the same timespan speaks to the enduring relevance ...
Robert B. Sowby +2 more
doaj +1 more source
New Pulsars from an Arecibo Drift Scan Search
, 2000 We report the discovery of pulsars J0030+0451, J0711+0931, and J1313+0931 that were found in a search of 470 square degrees at 430 MHz using the 305m Arecibo telescope.
Alex Zepka +16 more
core +1 more source
Arthritis Care &Research, EarlyView.Objective We evaluated the role of 25‐hydroxyvitamin D (25[OH]D), prednisone, and other risk factors for bone mineral density (BMD) loss and osteoporosis in systemic lupus erythematosus (SLE). Methods We calculated the association between 25(OH)D levels and other potential risk factors and BMD measures (spine T scores) and osteoporosis (defined as a T ...
Nima Madanchi +4 more
wiley +1 more source