Results 1 to 10 of about 1,781,612 (307)

Study of Interactions of an Anticancer Drug Neratinib With Bovine Serum Albumin: Spectroscopic and Molecular Docking Approach

Frontiers in Chemistry, 2018
Binding of therapeutic agents to plasma proteins, particularly to serum albumin, provides valuable information in the drug development. This study was designed to evaluate the binding interaction of neratinib with bovine serum albumin (BSA).
Tanveer A. Wani, Ahmed H. Bakheit, Ahmed H. Bakheit, M. A. Abounassif, Seema Zargar   +4 more
doaj   +1 more source

Study of binding interaction of rivaroxaban with bovine serum albumin using multi-spectroscopic and molecular docking approach

Chemistry Central Journal, 2017
Background Rivaroxaban is a direct inhibitor of coagulation factor Xa and is used for venous thromboembolic disorders. The rivaroxaban interaction with BSA was studied to understand its PK and PD (pharmacokinetics and pharmacokinetics) properties.
Tanveer A. Wani, Haitham AlRabiah, Ahmed H. Bakheit, Mohd Abul Kalam, Seema Zargar   +4 more
doaj   +1 more source

Increase in serum albumin concentration is associated with prediabetes development and progression to overt diabetes independently of metabolic syndrome. [PDF]

PLoS ONE, 2017
Serum albumin concentration is associated with both type 2 diabetes and metabolic syndrome (MetS). We sought to investigate whether baseline serum albumin and change in serum albumin could be independent risk factors for prediabetes in subjects without ...
Ji Eun Jun, Seung-Eun Lee, You-Bin Lee, Jae Hwan Jee, Ji Cheol Bae, Sang-Man Jin, Kyu Yeon Hur, Moon-Kyu Lee, Jae Hyeon Kim   +8 more
doaj   +1 more source

COMPARISON OF ROLE OF SERUM- ASCITES ALBUMIN GRADIENT AND ASCITIC FLUID TOTAL PROTEIN IN LIVER CIRRHOSIS PATIENTS

Pakistan Armed Forces Medical Journal, 2010
Objective: To compare the diagnostic sensitivity of serum/ ascites albumin gradient and ascitic fluid total protein in liver cirrhosis patients, using ultrasosnography as gold standard. Study Design: Validation Study.
Muhammad Younas, Abdus Sattar, Rizwan Hashim, Aamir Ijaz, Muhammad Dilawar, Asif Ali, Sayed Mohsin Manzoor, Farooq Ahmad Khan   +7 more
doaj   +1 more source

Relationship Between Serum Albumin and Risk of Atrial Fibrillation: A Dose-Response Meta-Analysis

Frontiers in Nutrition, 2021
Background: The dose–response association between serum albumin and atrial fibrillation is not well known. This study aims to assess the relationship between albumin and atrial fibrillation and the potential dose–response effect.Methods: Studies reported
Yali Wang, Peng Du, Qi Xiao, Jianfeng Li, Xiao Liu, Xiao Liu, Jinfeng Tan, Xingjian Zhang   +7 more
doaj   +1 more source

Association Between Serum Albumin Levels and Clinical Outcomes in Burn Patients: A Single-center Retrospective Analysis [PDF]

Bulletin of Emergency and Trauma
Objectives: Severe burns often result in significant intravascular albumin loss, leading to hypoalbuminemia. This study aimed to evaluate the association between serum albumin levels and clinical outcomes in burn patients.Methods: A retrospective, single-
Maryam Ramezanian, Parissa Bagheri, Cyrus Emir Alavi, Mohaya Farzin, MohammadReza Mobayen, Moein Moghaddam Ahmadi, Mohammad Tolouei, Siamak Rimaz, Mehdi Karimian, Hojat Eftekhari, Kiana Baghi, Ali Shabbak   +11 more
doaj   +1 more source

The relationship between serum albumin and prostate-specific antigen: A analysis of the National Health and Nutrition Examination Survey, 2003–2010

Frontiers in Public Health, 2023
BackgroundPrevious studies have shown that serum albumin is associated with prostate cancer (PCa), but not with prostate-specific antigen (PSA) levels in populations without PCa history.
Kailiang Xu, Youji Yan, Cong Cheng, Shiqin Li, Yixiang Liao, Jinmin Zeng, Zhongjun Chen, Jiajie Zhou   +7 more
doaj   +1 more source

Hubungan antara Kadar Serum Albumin Awal dengan Lama Rawat Inap dan Status Pulang Pasien Dewasa di Rumah Sakit

Jurnal Gizi Klinik Indonesia, 2004
Background: Several community studies have reported a relationship between a low serum albumin level and increased risk of hospital death, nosocomial infection, and length of stay. But this kind of study is still lacking in Indonesia.
Weni Kurdanti, Hamam Hadi, Susetyowati Susetyowati   +2 more
doaj   +1 more source

Anionic Calixarene-Capped Silver Nanoparticles Show Species-Dependent Binding to Serum Albumins

Molecules, 2013
The anionic calixarenes para-sulphonatocalix[4]arene and 1,3-di-Ophosphonatocalix[ 4]arene, have been used to cap silver nanoparticles. The binding of these functional particles with regard to various serum albumins (bovine serum albumin, human serum ...
Anthony W. Coleman, Florent Perret, Arnaud Brioude, Beomjoon Kim, Yannick Tauran   +4 more
doaj   +1 more source

The Minimal Effect of Linker Length for Fatty Acid Conjugation to a Small Protein on the Serum Half-Life Extension

Biomedicines, 2020
Conjugation of serum albumin or one of its ligands (such as fatty acid) has been an effective strategy to prolong the serum half-lives of drugs via neonatal Fc receptor (FcRn)–mediated recycling of albumin.
Jinhwan Cho, Junyong Park, Giyoong Tae, Mi Sun Jin, Inchan Kwon   +4 more
doaj   +1 more source