Binding of therapeutic agents to plasma proteins, particularly to serum albumin, provides valuable information in the drug development. This study was designed to evaluate the binding interaction of neratinib with bovine serum albumin (BSA).
Tanveer A. Wani +4 more
doaj +1 more source
Ursodeoxycholic acid improves bilirubin but not albumin in primary biliary cirrhosis: further evidence for nonefficacy. [PDF]
BACKGROUND/AIM: In randomised controlled trials (RCTs) of ursodeoxycholic acid (UDCA), although serum bilirubin is frequently reduced, its effect on disease progression and mortality is unclear.
Burroughs, Andrew K +5 more
core +3 more sources
Background Rivaroxaban is a direct inhibitor of coagulation factor Xa and is used for venous thromboembolic disorders. The rivaroxaban interaction with BSA was studied to understand its PK and PD (pharmacokinetics and pharmacokinetics) properties.
Tanveer A. Wani +4 more
doaj +1 more source
Increase in serum albumin concentration is associated with prediabetes development and progression to overt diabetes independently of metabolic syndrome. [PDF]
Serum albumin concentration is associated with both type 2 diabetes and metabolic syndrome (MetS). We sought to investigate whether baseline serum albumin and change in serum albumin could be independent risk factors for prediabetes in subjects without ...
Ji Eun Jun +8 more
doaj +1 more source
State of Harmonization of 24 Serum Albumin Measurement Procedures and Implications for Medical Decisions [PDF]
BACKGROUND: Measurements of serum and plasma albumin are widely used in medicine, including as indicators of quality of patient care in renal dialysis centers.
Bachmann, Lorin M. +4 more
core +2 more sources
Binding of bromocresol green and bromocresol purple to albumin in hemodialysis patients [PDF]
BACKGROUND: Colorimetric albumin assays based on binding to bromocresol purple (BCP) and bromocresol green (BCG) yield different results in chronic kidney disease. Altered dye binding of carbamylated albumin has been suggested as a cause.
Delanghe, Joris +8 more
core +1 more source
BackgroundPrevious studies have shown that serum albumin is associated with prostate cancer (PCa), but not with prostate-specific antigen (PSA) levels in populations without PCa history.
Kailiang Xu +7 more
doaj +1 more source
Relationship Between Serum Albumin and Risk of Atrial Fibrillation: A Dose-Response Meta-Analysis
Background: The dose–response association between serum albumin and atrial fibrillation is not well known. This study aims to assess the relationship between albumin and atrial fibrillation and the potential dose–response effect.Methods: Studies reported
Yali Wang +7 more
doaj +1 more source
Correlation Between Serum Albumin Level and Degree of Esophageal Varices in Patients with Liver Cirrhosis [PDF]
Background: It has not been clear about how often the patient should have esophago- gastroduodenoscopy (EGD) screening for esophageal varices (EV) detection and there is only some data that demonstrates the correlation between the degree of EV and non ...
Ariawan, Y. (Yuna) +5 more
core +1 more source
Association Between Serum Albumin Levels and Clinical Outcomes in Burn Patients: A Single-center Retrospective Analysis [PDF]
Objectives: Severe burns often result in significant intravascular albumin loss, leading to hypoalbuminemia. This study aimed to evaluate the association between serum albumin levels and clinical outcomes in burn patients.Methods: A retrospective, single-
Maryam Ramezanian +11 more
doaj +1 more source

