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Post-Translational Modifications and Functional Heterogeneity of Human Serum Albumin Formulations [PDF]

open access: yesToxins
Human serum albumin (HSA) is the most abundant plasma protein and plays essential roles in regulating oncotic pressure, transporting endogenous and exogenous compounds, and maintaining redox balance.
Roko Gladović   +3 more
doaj   +2 more sources

Spectroscopic Technique-Based Comparative Investigation on the Interaction of Theaflavins with Native and Glycated Human Serum Albumin

open access: yesMolecules, 2019
Theaflavin is a kind of multi-pharmacological and health beneficial black tea factor. The aim of this study is to investigate the mechanisms by which theaflavin interacts with glycosylated and non-glycosylated serum albumins and compares their binding ...
Jinhui Xu   +3 more
doaj   +3 more sources

Development of Human Serum Albumin-Based Hydrogels for Potential Use as Wound Dressings [PDF]

open access: yesGels
Protein-based materials such as human serum albumin (HSA) have demonstrated significant potential for the development of novel wound management materials.
Inna Zharkova   +5 more
doaj   +2 more sources

Diene-Extended Chalcones Enable Red Fluorescence Detection of Human Serum Albumin Through FA1 Binding [PDF]

open access: yesBiosensors
Fluorescent molecular probes for selective and real-time detection of human serum albumin (HSA) protein in urine and blood have important applications in clinical diagnostics for various diseases.
Brian Corbin   +4 more
doaj   +2 more sources

Single-center analysis of the inappropriate use of human albumin and nutritional support in hospitalized patients with hypoproteinemia in China

open access: yesJournal of International Medical Research, 2021
Background This study used single-center analysis of human serum albumin clinical usage and enteral-parenteral nutritional support to establish clinical application standards for the rational use of human serum albumin.
Jin Zhang, ZheTao Zhang, TianLu Shi
doaj   +1 more source

PEGylated Human Serum Albumin: Review of PEGylation, Purification and Characterization Methods [PDF]

open access: yesAdvanced Pharmaceutical Bulletin, 2016
Human serum albumin (HSA) is a non-glycosylated, negatively charged protein (Mw: about 65-kDa) that has one free cystein residue (Cys 34), and 17 disulfide bridges that these bridges have main role in its stability and longer biological life-time (15 to ...
Parvin Akbarzadehlaleh   +4 more
doaj   +1 more source

Effects of black cumin-based antimalarial drug loaded with nano-emulsion of bovine and human serum albumins by spectroscopic and molecular docking studies

open access: yesHeliyon, 2023
The growing understanding of nanoemulsion biomedical applications necessitates a basic understanding of protein–drug-loaded nanoemulsion interaction. In our present study, we investigated the binding interactions of Mefloquine (MEF)-loaded black cumin ...
Priyadarshini Mohapatra   +1 more
doaj   +1 more source

99mTc-GSA scintigraphy for assessing the functional volume ratio of the future liver remnant in the routine practice of liver resection

open access: yesSurgery Open Science, 2022
Background: The significance of incorporating regional functional heterogeneity assessment by liver scintigraphy into the calculation of the future liver remnant has been reported.
Masatake Iida, MD, PhD   +6 more
doaj   +1 more source

Reversible Dimerization of Human Serum Albumin

open access: yesMolecules, 2020
Pulsed Dipolar Spectroscopy (PDS) methods of Electron Paramagnetic Resonance (EPR) were used to detect and characterize reversible non-covalent dimers of Human Serum Albumin (HSA), the most abundant protein in human plasma.
Alexey Chubarov   +8 more
doaj   +1 more source

Relationship between human serum albumin and in-hospital mortality in critical care patients with chronic obstructive pulmonary disease

open access: yesFrontiers in Medicine, 2023
BackgroundThe relationship between human serum albumin levels and the prognosis of critical care patients with chronic obstructive pulmonary disease (COPD) remains controversial.ObjectiveTo investigate the relationship between serum albumin levels and in-
Ma Ling   +7 more
doaj   +1 more source

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