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Prevention of Protein Glycation by Natural Compounds [PDF]

open access: yesMolecules, 2015
Non-enzymatic protein glycosylation (glycation) contributes to many diseases and aging of organisms. It can be expected that inhibition of glycation may prolong the lifespan.
Izabela Sadowska-Bartosz   +1 more
exaly   +4 more sources

Advanced Glycation End Products and Inflammation in Type 1 Diabetes Development

open access: yesCells, 2022
Type 1 diabetes (T1D) is an autoimmune disease in which the β-cells of the pancreas are attacked by the host’s immune system, ultimately resulting in hyperglycemia. It is a complex multifactorial disease postulated to result from a combination of genetic
Chenping Du   +5 more
doaj   +1 more source

Higher Hepcidin Levels in Adolescents with Obesity Are Associated with Metabolic Syndrome Dyslipidemia and Visceral Fat

open access: yesAntioxidants, 2021
Tightly regulated iron metabolism prevents oxidative stress. Hepcidin is a hormone that regulates iron flow in plasma; its production is induced by an iron overload and by inflammation.
Reyna Rodríguez-Mortera   +4 more
doaj   +1 more source

The AGE receptor, OST48 drives podocyte foot process effacement and basement membrane expansion (alters structural composition)

open access: yesEndocrinology, Diabetes & Metabolism, 2021
Aims The accumulation of advanced glycation end products is implicated in the development and progression of diabetic kidney disease. No study has examined whether stimulating advanced glycation clearance via receptor manipulation is reno‐protective in ...
Aowen Zhuang   +10 more
doaj   +1 more source

Biophysical Characterisation of Amadori Modified Human Serum Albumin: A Prognostic Biomarker for Diabetic Complications [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2022
Introduction: Glycation of biological macromolecules particularly protein leads to the generation of early and Advanced Glycation End (AGE) products. The interest in early glycation of protein is driven due to the fact of Amadori modified proteins having
Binish Arif   +4 more
doaj   +1 more source

Correlation between saliva glycated and blood glycated proteins [PDF]

open access: yesEnvironmental Health and Preventive Medicine, 2003
Blood and saliva samples were obtained to examine if there is a correlation between saliva glycated protein and blood glycated protein.Blood and saliva samples of 51 male workers were collected. The fructosamine and hydrazine methods were used to measure saliva glycated protein.
Ichiro, Nakamoto   +3 more
openaire   +2 more sources

Alpha cell receptor for advanced glycation end products associate with glucagon expression in type 1 diabetes

open access: yesScientific Reports, 2023
Hypoglycemia in type 1 diabetes associates with changes in the pancreatic islet α cells, where the receptor for advanced glycation end products (RAGE) is highly expressed.
Sherman S. Leung   +11 more
doaj   +1 more source

Effect of transferrin glycation induced by high glucose on HK-2 cells in vitro

open access: yesFrontiers in Endocrinology, 2023
Background and objectiveGlycation is a common post-transcriptional modification of proteins. Previous studies have shown that advanced glycation end modified transferrin (AGE-Tf) levels in diabetic rat kidney tissues were increased; however, its role in ...
Yanqi Ma   +7 more
doaj   +1 more source

Elevated hemoglobin glycation index identify non-diabetic individuals at increased risk of kidney dysfunction [PDF]

open access: yes, 2017
Hemoglobin glycation index (HGI), calculated as the difference between the observed value of HbA1 and the predicted HbA1c based on plasma glucose concentration, is a measure of the individual tendency toward non-enzymatic hemoglobin glycation which has ...
Andreozzi F   +6 more
core   +3 more sources

Glycated Tryptophan PHP-THβC Incorporated into Various Chicken Embryonic Cells Constitutes Cellular Proteins

open access: yesThe Journal of Poultry Science, 2021
Glycation is a non-enzymatic reaction, and amino acids are glycated by glucose in vivo. Tryptophan is glycated with glucose to form two types of glycated compounds, tryptophan-Amadori product and (1R, 3S)-1-(D-gluco-1, 2, 3, 4, 5-pentahydroxypentyl)-1, 2,
Ryosuke Makino, Kayoko Abe, Kazumi Kita
doaj   +1 more source

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