Carbonyl Stress in Red Blood Cells and Hemoglobin
Antioxidants, 2021 The paper overviews the peculiarities of carbonyl stress in nucleus-free mammal red blood cells (RBCs). Some functional features of RBCs make them exceptionally susceptible to reactive carbonyl compounds (RCC) from both blood plasma and the intracellular
Olga V. Kosmachevskaya +2 more
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NMR analysis of synthetic human serum albumin alpha-helix 28 identifies structural distortion upon amadori modification [PDF]
, 2005 The non-enzymatic reaction between reducing sugars and long-lived proteins in vivo results in the formation of glycation and advanced glycation end products, which alter the properties of proteins including charge, helicity, and their tendency to ...
Howard, Mark J. +1 more
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Oxidative stress, protein glycation and nutrition – interactions relevant to health and disease throughout the lifecycle [PDF]
, 2014 Protein glycation has been studied for over a century now and plays an important role in disease pathogenesis throughout the lifecycle. Strongly related to diabetic complications, glycation of Hb has become the gold standard method for diabetes diagnosis
American Diabetes +17 more
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Paraoxonase 1, HDL Subclasses and Post Surgery Acute Inflammation: A Pilot Study
Antioxidants, 2019 High density lipoproteins (HDL) structure and function studies are needed to better understand the heterogeneous nature of the HDL particle, and its interaction with associated proteins such as apolipoprotein A-1 (ApoA-1), paraoxonase 1 (PON1) and the ...
Yasmin Bains +3 more
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Albumin Abundance and Its Glycation Status Determine Hemoglobin Glycation [PDF]
ACS Omega, 2018 Diabetes diagnosis and management majorly depend upon the measurement of glycated hemoglobin (HbA1c) levels. Various factors influence HbA1c levels such as the use of various analytical methods and the presence of various clinical conditions. Plasma albumin levels were known to be negatively associated with HbA1c.
Mashanipalya G. Jagadeeshaprasad +3 more
openaire +3 more sources
Soluble levels of receptor for advanced glycation endproducts and dysfunctional high-density lipoprotein in persons infected with human immunodeficiency virus: ACTG NWCS332. [PDF]
, 2018 The role of high-density lipoprotein (HDL) function and advanced glycation end products (AGEs) in HIV-related atherosclerotic cardiovascular disease (CVD) is unclear.
Aberg, Judith A +5 more
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The critical role of methylglyoxal and glyoxalase 1 in diabetic nephropathy [PDF]
, 2013 The discovery of increased formation of methylglyoxal (MG) by cell metabolism in high glucose concentration in vitro suggested possible relevance to diabetes and diabetes complications (1,2).
Rabbani, Naila, Thornalley, Paul J.
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Pharmacologic approaches against advanced glycation end products (ages) in diabetic cardiovascular disease [PDF]
, 2015 Advanced Glycation End-Products (AGEs) are signaling proteins associated to several vascular and neurological complications in diabetic and non-diabetic patients.
Avtaar Singh, Sanjeet Singh +6 more
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Glucose and glycogen in the diabetic kidney: Heroes or villains?
EBioMedicine, 2019 Glucose metabolism in the kidney is currently foremost in the minds of nephrologists, diabetologists and researchers globally, as a result of the outstanding success of SGLT2 inhibitors in reducing renal and cardiovascular disease in individuals with ...
Mitchell A. Sullivan +1 more
doaj +1 more source
Diabetes & Vascular Disease Research, 2020 Advanced glycation end-products, especially toxic advanced glycation end-products derived from glyceraldehyde (advanced glycation end-product-2) and glycolaldehyde (advanced glycation end-product-3), are biologically reactive compounds associated with ...
Takashi Nishinaka +7 more
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