Results 11 to 20 of about 4,588 (217)

Glucose and glycogen in the diabetic kidney: Heroes or villains?

EBioMedicine, 2019
Glucose metabolism in the kidney is currently foremost in the minds of nephrologists, diabetologists and researchers globally, as a result of the outstanding success of SGLT2 inhibitors in reducing renal and cardiovascular disease in individuals with ...
Mitchell A. Sullivan, Josephine M. Forbes   +1 more
doaj   +1 more source

A comparative study of sulphated polysaccharide effects on advanced glycation end-product uptake and scavenger receptor class A level in macrophages

Diabetes & Vascular Disease Research, 2020
Advanced glycation end-products, especially toxic advanced glycation end-products derived from glyceraldehyde (advanced glycation end-product-2) and glycolaldehyde (advanced glycation end-product-3), are biologically reactive compounds associated with ...
Takashi Nishinaka, Shuji Mori, Yui Yamazaki, Atsuko Niwa, Hidenori Wake, Tadashi Yoshino, Masahiro Nishibori, Hideo Takahashi   +7 more
doaj   +1 more source

Identification of Antiglycative Compounds in Japanese Red Water Pepper (Red Leaf Variant of the Persicaria hydropiper Sprout)

Molecules, 2018
Glycation, the nonenzymatic reaction between proteins and excess blood sugar, is implicated in multiple disorders and occurs via the formation and accumulation of advanced glycation end products (AGEs).
Wakako Takabe, Taiki Yamaguchi, Hideharu Hayashi, Natsuhiko Sugimura, Masayuki Yagi, Yoshikazu Yonei   +5 more
doaj   +1 more source

Glycated albumin and glycated hemoglobin- A comparison

International Journal of Biomedical Research, 2013
The progressive complications of unmanaged diabetes include heart disease, blindness, kidney failure, amputation of extremities due to circulation problems, and nerve disorders, as well as other chronic conditions. Decades of research have established that prolonged exposure to excess glucose is the cause of diabetes complications, and that long-term ...
Mukherjee, Brijesh, Patra, Saurav, Das, Ashok Kumar   +2 more
openaire   +3 more sources

d-Galactose Decreases Anion Exchange Capability through Band 3 Protein in Human Erythrocytes

Antioxidants, 2020
d-Galactose (d-Gal), when abnormally accumulated in the plasma, results in oxidative stress production, and may alter the homeostasis of erythrocytes, which are particularly exposed to oxidants driven by the blood stream.
Alessia Remigante, Rossana Morabito, Sara Spinelli, Vincenzo Trichilo, Saverio Loddo, Antonio Sarikas, Silvia Dossena, Angela Marino   +7 more
doaj   +1 more source

Antiglycation potential of commercial available extracts of two Indian medicinal plants: Pterocarpus marsupium and Artocarpus lakoocha using advanced glycation end products (AGE) competitive fluorescence assay

Cogent Food & Agriculture, 2021
Glycation is a non-enzymatic biochemical reaction between reducing sugars and amino acids, causing the crosslinking and rearrangement of glycated proteins, leading to irreversible formation of Advanced Glycation End products (AGEs).
Alpana Pande, Lakshmi Mundkur, Anurag Pande, Sarang Bani, Muhammed Majeed   +4 more
doaj   +1 more source

The Effect of UV Irradiation on Vitamin D₂ Content and Antioxidant and Antiglycation Activities of Mushrooms

Foods, 2020
Mushroom irradiation has been considered a sustainable process to generate high amounts of vitamin D2 due to the role of this vitamin for human health and of the global concerns regarding its deficient or inadequate intake.
Francesca Gallotti, Vera Lavelli
doaj   +1 more source

Gut Metabolism of Sugars: Formation of Glycotoxins and Their Intestinal Absorption

Diabetology, 2022
Glycotoxins include the group of advanced glycation end-products (AGEs) and their precursors, most of them highly reactive intermediary compounds of sugar metabolism. Glycotoxins and products of the Maillard reaction are present in high concentrations in
Tamaeh Monteiro-Alfredo, Paulo Matafome
doaj   +1 more source

Stability and Antiglycoxidant Potential of Bilberry Anthocyanins in Simulated Gastrointestinal Tract Model

Foods, 2020
Anthocyanins from Vaccinium myrtillus fruits have been reported in vitro to exert potent radical scavenging and antiglycation activities. However, the physiological relevance of such properties remains unclear given the potential susceptibility of ...
Didier Fraisse, Alexis Bred, Catherine Felgines, François Senejoux   +3 more
doaj   +1 more source

Açaì (Euterpe oleracea) Extract Protects Human Erythrocytes from Age-Related Oxidative Stress

Cells, 2022
Aging is a process characterised by a general decline in physiological functions. The high bioavailability of reactive oxygen species (ROS) plays an important role in the aging rate.
Alessia Remigante, Sara Spinelli, Elisabetta Straface, Lucrezia Gambardella, Daniele Caruso, Giuseppe Falliti, Silvia Dossena, Angela Marino, Rossana Morabito   +8 more
doaj   +1 more source