Resveratrol protects mouse oocytes from methylglyoxal-induced oxidative damage. [PDF]
PLoS ONE, 2013 Methylglyoxal, a reactive dicarbonyl compound, is mainly formed from glycolysis. Methylglyoxal can lead to the dysfunction of mitochondria, the depletion of cellular anti-oxidation enzymes and the formation of advanced glycation ends.
Yu Liu +10 more
doaj +2 more sources
Alu antisense RNA ameliorates methylglyoxal-induced human lens epithelial cell apoptosis by enhancing antioxidant defense [PDF]
International Journal of Ophthalmology, 2023 AIM: To determine whether an antisense RNA corresponding to the human Alu transposable element (Aluas RNA) can protect human lens epithelial cells (HLECs) from methylglyoxal-induced apoptosis.
Pei-Yuan Wu +10 more
doaj +1 more source
Hydrogen sulfide releasing aspirin, ACS14, attenuates high glucose-induced increased methylglyoxal and oxidative stress in cultured vascular smooth muscle cells. [PDF]
PLoS ONE, 2014 Hydrogen sulfide is a gasotransmitter with vasodilatory and anti-inflammatory properties. Aspirin is an irreversible cyclooxygenase inhibitor anti-inflammatory drug.
Qian Huang +4 more
doaj +1 more source
Molecules, 2023 Glyoxal and methylglyoxal are important volatile organic compounds in the atmosphere. The gas–particle partitioning of these carbonyl compounds makes significant contributions to O3 formation.
Weining Qi +11 more
doaj +1 more source
A quantification method for heat-decomposable methylglyoxal oligomers and its application on 1,3,5-trimethylbenzene SOA [PDF]
Atmospheric Chemistry and Physics, 2017 Methylglyoxal forms oligomeric compounds in the atmospheric aqueous particle phase, which could establish a significant contribution to the formation of aqueous secondary organic aerosol (aqSOA).
M. Rodigast, A. Mutzel, H. Herrmann
doaj +1 more source
Methylglyoxal induces systemic symptoms of irritable bowel syndrome. [PDF]
PLoS ONE, 2014 Patients with irritable bowel syndrome (IBS) show a wide range of symptoms including diarrhea, abdominal pain, changes in bowel habits, nausea, vomiting, headache, anxiety, depression and cognitive impairment.
Shuang Zhang +5 more
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Chemical insights, explicit chemistry, and yields of secondary organic aerosol from OH radical oxidation of methylglyoxal and glyoxal in the aqueous phase [PDF]
Atmospheric Chemistry and Physics, 2013 Atmospherically abundant, volatile water-soluble organic compounds formed through gas-phase chemistry (e.g., glyoxal (C2), methylglyoxal (C3), and acetic acid) have great potential to form secondary organic aerosol (SOA) via aqueous chemistry in clouds ...
Y. B. Lim, Y. Tan, B. J. Turpin
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Increased methylglyoxal formation with upregulation of renin angiotensin system in fructose fed Sprague Dawley rats. [PDF]
PLoS ONE, 2013 The current epidemic of obesity and type 2 diabetes is attributed to a high carbohydrate diet, containing mainly high fructose corn syrup and sucrose. More than two thirds of diabetic patients have hypertension.
Indu Dhar +3 more
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Ferricytochrome (c) directly oxidizes aminoacetone to methylglyoxal, a catabolite accumulated in carbonyl stress. [PDF]
PLoS ONE, 2013 Age-related diseases are associated with increased production of reactive oxygen and carbonyl species such as methylglyoxal. Aminoacetone, a putative threonine catabolite, is reportedly known to undergo metal-catalyzed oxidation to methylglyoxal, NH4 ...
Adriano Sartori +8 more
doaj +1 more source
Mechanisms leading to oligomers and SOA through aqueous photooxidation: insights from OH radical oxidation of acetic acid and methylglyoxal [PDF]
Atmospheric Chemistry and Physics, 2012 Previous experiments have demonstrated that the aqueous OH radical oxidation of methylglyoxal produces low volatility products including pyruvate, oxalate and oligomers.
Y. Tan +4 more
doaj +1 more source