Results 31 to 40 of about 12,428 (180)
Quantification of Methylglyoxal Levels in Cowpea Leaves in Response to Cowpea Aphid Infestation
Bio-Protocol, 2020 Aphids are a serious pest of crops across the world. Aphids feed by inserting their flexible hypodermal needlelike mouthparts, or stylets, into their host plant tissues.
Jacob MacWilliams +4 more
doaj +1 more source
Frontiers in Endocrinology, 2022 Methylglyoxal, a major precursor of advanced glycation end products, is elevated in the plasma of patients with type 2 diabetes mellitus. Islet β-cell function was recently shown to be regulated by N6-methyladenosine (m6A), an RNA modification consisting
Yi Cheng +12 more
doaj +1 more source
EBioMedicineSummary: Background: We previously identified methylglyoxal as a biomarker for early identification and outcome prediction in human sepsis. We hypothesised that methylglyoxal causally impacts disease severity, and the methylglyoxal-scavenging dipeptide ...
Thomas Schmoch +12 more
doaj +1 more source
Бюллетень сибирской медицины, 2022 The aim of this work was to study the levels of podocalyxin and β-2-microglobulin and parameters of lipid metabolism and carbonyl stress in type 1 diabetes mellitus (T1DM) patients with different levels of albuminuria.Materials and methods.
M. A. Darenskaya +6 more
doaj +1 more source
Frontiers in Cardiovascular Medicine, 2022 BackgroundHeightened glycolytic flux is associated with right ventricular (RV) dysfunction in pulmonary arterial hypertension (PAH). Methylglyoxal, a glycolysis byproduct, is a highly reactive dicarbonyl that has toxic effects via non-enzymatic post ...
Sasha Z. Prisco +8 more
doaj +1 more source
The effect of methylglyoxal on the glycolytic enzymes [PDF]
FEBS Letters, 1980 with free arginine and have found that the reaction rate, much faster with methylglyoxal than with phenylglyoxal, depends on the buffer type and increases by increasing the pH. Data on the inactivation mechanism of aldolase and glyceraldehyde-3-phosphate dehydrogenase by methyl- glyoxal have shown that one arginine residue is involved in the ...
Leoncini, Giuliana +2 more
openaire +2 more sources
Advanced Science, EarlyView.Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang +32 more
wiley +1 more source
Seasonal in situ observations of glyoxal and methylglyoxal over the temperate oceans of the Southern Hemisphere [PDF]
Atmospheric Chemistry and Physics, 2015 The dicarbonyls glyoxal and methylglyoxal have been measured with 2,4-dinitrophenylhydrazine (2,4-DNPH) cartridges and high-performance liquid chromatography (HPLC), optimised for dicarbonyl detection, in clean marine air over the temperate Southern ...
S. J. Lawson +7 more
doaj +1 more source
Probing Electrocatalyst Design for Product Selectivity in CO2 Reduction
Advanced Science, EarlyView.Selective CO2 electroreduction is controlled by catalyst structure, dynamic surface reconstruction, adsorbate interactions, and reaction microenvironment. This review summarizes Cu‐ and non‐Cu‐based catalysts, single‐atom and molecular systems, degradation pathways, and operando/computational strategies for steering CO2RR toward hydrocarbons ...
Suvodeep Sen +5 more
wiley +1 more source
The Glyoxalase System—New Insights into an Ancient Metabolism
Antioxidants, 2020 The glyoxalase system was discovered over a hundred years ago and since then it has been claimed to provide the role of an indispensable enzyme system in order to protect cells from a toxic byproduct of glycolysis.
Jakob Morgenstern +3 more
doaj +1 more source