Results 51 to 60 of about 18,817 (217)
Neuroprotective Effect of Sulforaphane against Methylglyoxal Cytotoxicity [PDF]
, 2015 Glycation, an endogenous process that leads to the production of advanced glycation end products (AGEs), plays a role in the etiopathogenesis of different neurodegenerative diseases, such as Alzheimer's disease (AD).
ANGELONI, Cristina +5 more
core +1 more source
Methylglyoxal in Manuka Honey - Correlation with Antibacterial Properties
Czech Journal of Food Sciences, 2009 A perfect linear correlation was found for methylglyoxal levels in 61 samples of Manuka honey, ranging from 189 to 835 mg/kg, and the corresponding antibacterial activities of the samples, which were between 12.4% and 30.9% equivalent phenol ...
J. Atrott, T. Henle
doaj +1 more source
Foods, 2023 The contents of free and protein-bound advanced glycation end-products (AGEs) including Nε-carboxymethyllysine (CML) and Nε-carboxyethyllysine (CEL), along with glyoxal (GO), methylglyoxal (MGO), chemical components, and salt in commercially prepared and
Lihong Niu +4 more
doaj +1 more source
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Aims Chronic kidney disease (CKD) is a major complication of type 2 diabetes mellitus (T2DM), driven in part by oxidative stress and the accumulation of advanced glycation end products (AGEs). Oleanolic acid (OA), a natural triterpene present in olive‐derived matrices, may modulate AGE metabolism.
Aída García‐González +14 more
wiley +1 more source
, 2017 Diabetic retinopathy (DR) and age-related macular degeneration (AMD) are two important leading causes of acquired blindness in developed countries. As accumulation of advanced glycation end products (AGEs) in retinal pigment epithelial (RPE) cells plays ...
林琬琬 +1 more
core +1 more source
Carbonyl Stress in Red Blood Cells and Hemoglobin
Antioxidants, 2021 The paper overviews the peculiarities of carbonyl stress in nucleus-free mammal red blood cells (RBCs). Some functional features of RBCs make them exceptionally susceptible to reactive carbonyl compounds (RCC) from both blood plasma and the intracellular
Olga V. Kosmachevskaya +2 more
doaj +1 more source
Prebiotic aqueous reactions catalyzed by native nickel without hydrogen
The FEBS Journal, EarlyView.Serpentinizing (H2‐producing) hydrothermal vents are candidate environments for metabolic origin. They generate highly reducing conditions that convert CO2 to formate and methane in abiotic reactions resembling reactions of the acetyl‐CoA pathway of CO2 fixation. They also contain natural catalysts. Native nickel (Ni0), like Fe0, Co0, and their alloys,
Carolina Garcia Garcia +2 more
wiley +1 more source
Common pathways and outliers in glucose catabolism across Trypanosomatidae
The FEBS Journal, EarlyView.Trypanosomatid parasites, including Trypanosoma sp., Leishmania sp., Phytomonas sp., and Vickermania sp., share a common motif: a metabolism built around the glycosome, a unique peroxisome‐derived organelle housing the first steps of glycolysis. Yet, these organisms have evolved remarkably diverse strategies to catabolize glucose, excreting distinct ...
Fred R. Opperdoes +5 more
wiley +1 more source
The effect of methylglyoxal on the glycolytic enzymes [PDF]
FEBS Letters, 1980 with free arginine and have found that the reaction rate, much faster with methylglyoxal than with phenylglyoxal, depends on the buffer type and increases by increasing the pH. Data on the inactivation mechanism of aldolase and glyceraldehyde-3-phosphate dehydrogenase by methyl- glyoxal have shown that one arginine residue is involved in the ...
Leoncini, Giuliana +2 more
openaire +2 more sources
Methylglyoxal-Induced Glycation Affects Protein Topography
, 2003 Methylglyoxal is a metabolic byproduct that is elevated in diabetic tissue. We examined the effects of methylglyoxal on cytosolic aspartate aminotransferase (cAAT), which is an enzyme previously shown to be modified by glyceraldehyde, acrolein, and ...
Seidler, Norbert W. +1 more
core +1 more source