Results 61 to 70 of about 12,428 (180)

Boron Reduced Copper Excess-Induced Oxidative Damage in Citrus sinensis by Modulating Reactive Oxygen Species and Methylglyoxal Formation and Their Detoxification Systems

Antioxidants
Citrus is mainly cultivated in acid soil with low boron (B) and high copper (Cu). In this study, Citrus sinensis seedlings were submitted to 0.5 (control) or 350 μM Cu (Cu excess or Cu exposure) and 2.5, 10, or 25 μM B for 24 weeks.
Xu-Feng Chen, Huan-Huan Chen, Wei-Lin Huang, Wei-Tao Huang, Zeng-Rong Huang, Lin-Tong Yang, Xin Ye, Li-Song Chen   +7 more
doaj   +1 more source

The Circadian Oscillator Affects Both Glutathione Homeostasis and Its Response to Salt Stress in Arabidopsis thaliana

Plant, Cell &Environment, Volume 49, Issue 8, Page 5421-5434, August 2026.
ABSTRACT Glutathione, including reduced glutathione (GSH) and oxidized glutathione (GSSG), is the major non‐protein thiol‐based redox buffer. There are diurnal rhythms in total glutathione level and in this work, we investigate whether these oscillations might be indicative of circadian regulation of total glutathione homeostasis.
Desiré Cano‐Yelo, Raquel López‐Martínez, Francisca Sevilla, Alex A. R. Webb, Ana Jiménez, María Carmen Martí   +5 more
wiley   +1 more source

Immunoinflammatory Mechanisms and Biocompatibility of Bioactive Dental Biomaterials: From Fundamental Insights to Clinical Translation

Advanced Healthcare Materials, Volume 15, Issue 27, 17 July 2026.
Surface‐host dialogue at the implant interface governs biological fate and osseointegration. Surface physicochemical properties of titanium (Ti) dental implants, including microgrooves, nanopatterns, nanotopography, roughness, and wettability, modulate the initial adsorption of proteins and the formation of a dynamic biointerface.
Daniela Moreira Cunha, Amanda Paino Santana, Marta Maria Alves Pereira, Mariana Martins Guerreiro, Jose Mauro Granjeiro, Jamil Awad Shibli, Jeroen J. J. P. van den Beucken, Anton Sculean, Rafael Scaf de Molon, Erica Dorigatti de Avila   +9 more
wiley   +1 more source

Engineered AuNPs/fMWCNT Nanocomposite Electrodes for High‐Sensitivity Methylglyoxal Sensing in Saliva and Sweat for Non‐Invasive Diabetes Monitoring

Advanced Healthcare Materials, Volume 15, Issue 28, 24 July 2026.
An AuNPs/fMWCNT nanocomposite‐modified screen‐printed carbon electrode was engineered via sequential electrodeposition and integrated into a 3D‐printed microfluidic platform for ultrasensitive methylglyoxal detection. The non‐invasive sensing platform enables rapid analysis in saliva and sweat, highlighting strong potential for wearable point‐of‐care ...
Ahadul Amin Soshi, Md Younus Ali, Dadbeh Pazuki, Matiar M.R. Howlader   +3 more
wiley   +1 more source

Neuroprotection through flavonoid: Enhancement of the glyoxalase pathway

Redox Biology, 2018
The glyoxalase pathway functions to detoxify reactive dicarbonyl compounds, most importantly methylglyoxal. The glyoxalase pathway is an antioxidant defense mechanism that is essential for neuroprotection.
Joel R. Frandsen, Prabagaran Narayanasamy   +1 more
doaj   +1 more source

Chebulic Acid Prevents Methylglyoxal-Induced Mitochondrial Dysfunction in INS-1 Pancreatic β-Cells

Antioxidants, 2020
To investigate the anti-diabetic properties of chebulic acid (CA) associated with the prevention of methyl glyoxal (MG)-induced mitochondrial dysfunction in INS-1 pancreatic β-cells, INS-1 cells were pre-treated with CA (0.5, 1.0, and 2.0 μM) for 48 h ...
Hyun-jung Yoo, Chung-Oui Hong, Sang Keun Ha, Kwang-Won Lee   +3 more
doaj   +1 more source

The dataset of methylglyoxal activating p38 and p44/42 pathway in osteoclast

Data in Brief, 2019
Diabetes mellitus (DM) is a kind of chronic metabolic disease that could be characterized by uncontrollable high blood glucose (hyperglycemia) over a prolonged period and diverse complications in various organs.
Kwan Ming Lee, Cheuk Yan Lee, Ge Zhang, Aiping Lyu, Kevin Kin Man Yue   +4 more
doaj   +1 more source

Methylglyoxal metabolism in trypanosomes and leishmania

Seminars in Cell & Developmental Biology, 2011
Methylglyoxal is a toxic by-product of glycolysis and other metabolic pathways. In mammalian cells, the principal route for detoxification of this reactive metabolite is via the glutathione-dependent glyoxalase pathway forming d-lactate, involving lactoylglutathione lyase (GLO1; EC 4.4.1.5) and hydroxyacylglutathione hydrolase (GLO2; EC 3.2.1.6).
Wyllie, Susan, Fairlamb, Alan H.
openaire   +3 more sources

Determination of toxic α-dicarbonyl compounds in sesame oils using dispersive liquid–liquid microextraction coupled with gas chromatography–mass spectrometry

Food Chemistry: X
Glyoxal, methylglyoxal, and diacetyl are toxic α-dicarbonyl compounds found in heat-processed foods, including edible oils. Dispersive liquid–liquid microextraction was combined with gas chromatography mass spectrometry to determine the glyoxal ...
Jangho Lee, Tae Gyu Nam, Hyo-Kyoung Choi, Hae Won Jang   +3 more
doaj   +1 more source

Investigation of Methylglyoxal, soluble Receptor for Advanced Glycation End-products, and Malondialdehyde in Type 2 Diabetes Mellitus with and Without Cardiovascular Risk Factors

Diyala Journal of Medicine
Background: Type 2 diabetes mellitus is a chronic metabolic illness that significantly increases the probability of cardiovascular disorders among individuals with type 2 diabetes.
Weaam F. Hussien, Estabraq A. R. Al-Wasiti, Mahood. Sh. Khudair, Hayder A. AL-Aubaidy   +3 more
doaj   +1 more source