Results 81 to 90 of about 28,399 (260)
A novel mechanism of methylglyoxal cytotoxicity in prostate cancer cells
, 2013 Methylglyoxal is one of the most powerful glycating agents of proteins and other important cellular components and has been shown to be toxic to cultured cells.
ANTOGNELLI, Cinzia +3 more
core +1 more source
Plants, 2021 Methylglyoxal (MG) is the primary precursor of advanced glycation end products involved in the pathogenesis of inflammation and diabetes. A previous study in our laboratory found anti-inflammatory and anti-hyperglycemic effects of the polyphenol ...
Wen-Chang Chang +2 more
doaj +1 more source
bioRxiv, 2020 In Candida species, the transcription factor Mrr1 regulates azole resistance genes in addition to the expression of a suite of other genes including known and putative methylglyoxal reductases.
Amy R. Biermann +2 more
semanticscholar +1 more source
The FEBS Journal, EarlyView.In Colletotrichum acutatum species complex, conserved ring‐cleavage dioxygenases located adjacent to AA5_2 enzymes were investigated as potential redox partners. Biochemical analyses identified the dioxygenases as intradiol‐cleaving enzymes preferentially oxidizing methyl‐substituted catechols, while AA5_2 enzymes displayed weak alcohol oxidase ...
Radka Končitíková +7 more
wiley +1 more source
Methylglyoxal scavengers attenuate endothelial dysfunction induced by methylglyoxal and high concentrations of glucose [PDF]
British Journal of Pharmacology, 2010 BACKGROUND AND PURPOSEEndothelial dysfunction is a feature of hypertension and diabetes. Methylglyoxal (MG) is a reactive dicarbonyl metabolite of glucose and its levels are elevated in spontaneously hypertensive rats and in diabetic patients. We investigated if MG induces endothelial dysfunction and whether MG scavengers can prevent endothelial ...
Arti, Dhar +3 more
openaire +2 more sources
Methylglyoxal and the brain microcirculation:the source matters [PDF]
The small blood vessels in the brain are crucial for maintaining healthy brain function. When these vessels are affected by disease, a condition called cerebral small vessel disease, it is common in older adults.
Berends, Eline
core +1 more source
Dynamic memory in rodent C‐fibres and its impact on spinal nociceptive processing
The Journal of Physiology, EarlyView.Abstract figure legend Nociceptive C‐fibres display activity‐dependent slowing (ADS) whereby successive action potentials are conducted progressively slower thus regulating the temporal relay of pain signals. This study shows that the ADS induced by short stimulus trains (which mimic stimulus evoked firing, shown in orange) is modified by prior ...
Atanaska N. Velichkova, Carole Torsney
wiley +1 more source
The formation of methylglyoxal from triose phosphates [PDF]
European Journal of Biochemistry, 1993 In Krebs‐Ringer phosphate buffer, the rate of formation of methylglyoxal from glycerone phosphate and glyceraldehyde 3‐phosphate was first order with respect to the triose phosphate with rates constant values of 1.94 ± 0.02 × 10−5 s−1 (n= 18) and 1.54 ± 0.02 × 10−4 s−1 (n= 18) at 37°C, respectively. The rate of formation of methylglyoxal from glycerone
S A, Phillips, P J, Thornalley
openaire +2 more sources
Legume Science, Volume 8, Issue 4, December 2026.ABSTRACT Pea (Pisum sativum) is a nutrient‐rich crop that can provide essential nutrients needed for human and animal health. Improving its mineral concentration through genetic selection can enhance its nutritional value and help combat micronutrient deficiencies. This study aimed to investigate the genetic basis of the accumulation of eight minerals (
Maryam Bagheri +4 more
wiley +1 more source
Biological Flora of New Zealand 17: Kunzea ericoides (Myrtaceae), Kānuka
New Zealand Journal of Botany, Volume 64, Issue 4, December 2026.This review summarises the taxonomic status, morphology, physiology, ecology, plant communities, mycological, invertebrate and vertebrate interactions and human use of the New Zealand endemic tree Kunzea ericoides (A. Rich.) Joy Thomps. (kānuka) (Myrtaceae).
P. J. Bellingham +8 more
wiley +1 more source