Results 81 to 90 of about 16,994 (228)

Optimizing enzyme properties to enhance dihydroxyacetone production via methylglyoxal biosensor development

open access: yesMicrobial Cell Factories
Background Dihydroxyacetone (DHA) stands as a crucial chemical material extensively utilized in the cosmetics industry. DHA production through the dephosphorylation of dihydroxyacetone phosphate, an intermediate product of the glycolysis pathway in ...
Kaibo Zhang   +11 more
doaj   +1 more source

Boron Reduced Copper Excess-Induced Oxidative Damage in Citrus sinensis by Modulating Reactive Oxygen Species and Methylglyoxal Formation and Their Detoxification Systems

open access: yesAntioxidants
Citrus is mainly cultivated in acid soil with low boron (B) and high copper (Cu). In this study, Citrus sinensis seedlings were submitted to 0.5 (control) or 350 μM Cu (Cu excess or Cu exposure) and 2.5, 10, or 25 μM B for 24 weeks.
Xu-Feng Chen   +7 more
doaj   +1 more source

Ashwagandha Root Extract and Its Potential Modulation of CCN1‐Associated Pathways in Sensitive‐Skin Aging

open access: yesJournal of Cosmetic Dermatology, Volume 25, Issue 7, July 2026.
ABSTRACT Background Cellular Communication Network Factor 1 (CCN1) has been identified as a key regulator of oxidative stress‐induced skin aging and sensitivity. Ashwagandha root extract (ARE) is a promising candidate for modulating CCN1‐associated pathways. Aims To investigate whether ARE can mitigate sensitive‐skin aging by modulating CCN1 expression
Liying Kang   +13 more
wiley   +1 more source

Methylglyoxal Influences Development of Caenorhabditis Elegans via Heterochronic Pathway

open access: yes, 2017
Methylglyoxal is a highly reactive dicarbonyl compound, which is widely distributed in food products and beverages, and is particularly high in Manuka honey.
Wang, Jiaying
core   +1 more source

Facet and Phase Engineering of Single‐Crystalline Transition‐Metal Phosphide Electrocatalysts for Selective Electrochemical Reactions

open access: yesChemElectroChem, Volume 13, Issue 12, 17 June 2026.
Facet and phase engineering enables selective electrocatalysis in single‐crystalline transition‐metal phosphides by controlling surface termination, phase identity, and intermediate binding. This review connects noble metal benchmarks, phosphide phase evolution, synthetic growth principles, and electrode translation to guide rational catalyst design ...
Jieun Seo   +4 more
wiley   +1 more source

Chebulic Acid Prevents Methylglyoxal-Induced Mitochondrial Dysfunction in INS-1 Pancreatic β-Cells

open access: yesAntioxidants, 2020
To investigate the anti-diabetic properties of chebulic acid (CA) associated with the prevention of methyl glyoxal (MG)-induced mitochondrial dysfunction in INS-1 pancreatic β-cells, INS-1 cells were pre-treated with CA (0.5, 1.0, and 2.0 μM) for 48 h ...
Hyun-jung Yoo   +3 more
doaj   +1 more source

Chemical Syntheses of 3′ and 5′ Phosphorylated Oligonucleotides: An Overview

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 21, 4 June 2026.
This review provides an overview of the various chemical methods employed in the synthesis of oligonucleotides bearing a phosphate group at their 3′ or 5′ end. Notably, it presents modified phosphoramidites and supports developed for this purpose. Oligonucleotides (ON) with a phosphate monoester group at their 3′ or 5′ end have applications in many ...
Rémy Lartia
wiley   +1 more source

Neuroprotection through flavonoid: Enhancement of the glyoxalase pathway

open access: yesRedox Biology, 2018
The glyoxalase pathway functions to detoxify reactive dicarbonyl compounds, most importantly methylglyoxal. The glyoxalase pathway is an antioxidant defense mechanism that is essential for neuroprotection.
Joel R. Frandsen   +1 more
doaj   +1 more source

The Bactericidal Activity and Spore Inhibition Effect of Manuka Honey against Clostridioides Difficile

open access: yesAntibiotics, 2020
Clostridioides difficile colitis overgrowth occurs when the normal gut microbiome becomes disrupted, often due to antibiotics. Effective treatment remains elusive, due partly to the persistence of its spores in the gut.
Lillian Yu   +3 more
doaj   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

open access: yesFEBS Open Bio, Volume 16, Issue 6, Page 1150-1165, June 2026.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi   +7 more
wiley   +1 more source

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