Results 101 to 110 of about 16,994 (228)
Background: Type 2 diabetes mellitus is a chronic metabolic illness that significantly increases the probability of cardiovascular disorders among individuals with type 2 diabetes.
Weaam F. Hussien +3 more
doaj +1 more source
Nitrate (NO3–) and ammonium (NH4+) are prevalent nitrogen (N) sources for plants. Although NH4+ should be the preferred form of N from the energetic point of view, ammonium nutrition often exhibits adverse effects on plant physiological functions and ...
Klaudia Borysiuk +4 more
doaj +1 more source
Microbial Electrosynthesis Reshapes Energy Metabolism and Physiology in Clostridium ljungdahlii
Microbial electrosynthesis drives Clostridium ljungdahlii into a distinct stress‐associated physiological state, different from gas fermentation. Comparative multi‐omics and electron microscopy reveal physiological constraints that help explain the poor performance of MES.
Sara Al Sbei +8 more
wiley +1 more source
Endothelial dysfunction such as hyper permeability is one of the char acteristics in an earlystage of diabetic complicatio ns. Curcumin has been sho wn to inhibit the formation ofadv anced glycation end products (AGEs)and to trap meth yglyo xal (MGO) in ...
Te-Y u Hu +3 more
core +1 more source
Antiglycation Activity of Aucubin In Vitro and in Exogenous Methylglyoxal Injected Rats
Advanced glycation end products (AGEs) is a causative factor of various chronic diseases, including chronic kidney disease and atherosclerosis. AGE inhibitors, such as aminoguanidine and pyridoxamine, have the therapeutic activities for reversing the ...
Eunsoo Jung +4 more
doaj +1 more source
The blend enhanced antioxidation, anti‐glycation, autophagy and circadian regulation in cell and skin models. Key markers included mitochondrial ROS, γ‐H2AX, AGEs, ATP, melatonin, LC3 and SOD. Significant improvements were visualized via fluorescence and quantified with statistical markers.
Lina Wang +4 more
wiley +1 more source
A comparative study of methylglyoxal metabolism in trypanosomatids
The glyoxalase system, comprising the metalloenzymes glyoxalase I (GLO1) and glyoxalase II (GLO2), is an almost universal metabolic pathway involved in the detoxification of the glycolytic byproduct methylglyoxal to d-lactate.
Patterson, Stephen +3 more
core +1 more source
ABSTRACT The wound‐scratch assay is a widely used in vitro model for studying collective cell migration, a fundamental process contributing to wound closure and re‐epithelialisation. Owing to its simplicity, low cost, and adaptability, it has become a foundational tool for early‐stage wound‐healing research and therapeutic screening. The assay involves
Philisiwe F. Molefe +3 more
wiley +1 more source
Escherichia coli can survive methylglyoxal stress by modulating phosphorylation of a regulatory phosphotransferase system, which, in turn, regulates the activity of a potassium/proton antiporter. The constitutive potassium importer Trk also contributes to intracellular potassium levels.
Sara Alexander, Mark Goulian
wiley +1 more source
Adaptive response of human melanoma cells to methylglyoxal injury.
-The effects of methylglyoxal on the growth of a line of human melanoma cells are investigated. Methylglyoxal inhibits cell growth in a dose-dependent manner and causes an increase in glyceraldehyde 3-phosphate dehydrogenase, and glyoxalase 1 and ...
POMA AMMA +6 more
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