Results 121 to 130 of about 12,428 (180)

Mechanisms of Isoliquiritigenin Against Protein Glycation: A Comparative Study in PBS Solution and Crowding Environment. [PDF]

Foods
Wei Y, Gong D, Zhang G.
europepmc   +1 more source

Balancing the dual nature of glycotoxins: interplay of diet, digestion, and gut microbiome. [PDF]

Front Nutr
Semchyshyn H.
europepmc   +1 more source

Small-Molecule Sarco/Endoplasmic Reticulum Ca²⁺-ATPase Activators Reverse Methylglyoxal-Induced Inhibition through Nonantioxidant Mechanisms. [PDF]

ChemMedChem
Cruz-Cortés C, Micháliková S, Rezbáriková P, Espinoza-Fonseca LM, Viskupičová J.   +4 more
europepmc   +1 more source

Reactive carbonyl species in health and chronic disease: from methylglyoxal to an integrative network of metabolic regulation. [PDF]

Cardiovasc Diabetol
Li S, Nawroth PP, Kroll J.
europepmc   +1 more source

Effects of low intracellular glutathione and CbrA-CbrB-Crc signaling on methylglyoxal sensitivity in <i>Pseudomonas aeruginosa</i> LasR-deficient mutants. [PDF]

J Bacteriol
Altamirano A, Ruzic M, Cryan AE, Hogan DA.   +3 more
europepmc   +1 more source

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Ketogenic diet prevents methylglyoxal-evoked nociception by scavenging methylglyoxal

Pain, 2022
Abstract Methylglyoxal (MGO) is a reactive dicarbonyl byproduct of glycolysis implicated in a growing number of neuropathic pain conditions, including chemotherapy-induced peripheral neuropathy, diabetic peripheral neuropathy, and radiculopathy with lumbar disk herniation.
Jonathan D. Enders, Sarah Thomas, Matthew Taylor Swanson, Janelle M. Ryals, Douglas E. Wright   +4 more
openaire   +2 more sources

Methylglyoxal toxicity in mammals

Toxicology Letters, 1994
Although the interest is growing towards glyoxalases and methylglyoxal, their role in metabolism is still an enigma. In this paper, the effects of methylglyoxal in both in vivo and in vitro mammalian systems are reviewed and correlated with its interaction with macromolecules (nucleic acids, proteins).
Miklós Kalapos, M P Kalapos
exaly   +3 more sources

A fluorogenic assay for methylglyoxal

Biochemical Society Transactions, 2014
MG (methylglyoxal) is a potent glycating agent and an endogenous reactive dicarbonyl metabolite formed in all live cells and organisms. It is an important precursor of AGEs (advanced glycation end-products) and is implicated in aging and disease. MG is assayed by derivatization by 1,2-diaminobenzene derivatives in cell extracts.
Fozia, Shaheen, Anatoly, Shmygol, Naila, Rabbani, Paul J, Thornalley   +3 more
openaire   +2 more sources

The effect of methylglyoxal on actin

Biochemical and Biophysical Research Communications, 1981
Abstract Studying the gelation of Ehrlich ascites tumor cell extracts at various methyglyoxal concentrations, an increase of the gelled protein fraction, composed mainly of actin, was found at 10 −7 M to 10 −5 M. When methylglyoxal was added to intact tumor cells, the filamentous portion of cytoplasmic actin was increased at 10 −7 M to 10 −6 M ...
Fesus, L, Muszbek, L, Laki, K
openaire   +2 more sources