Results 131 to 140 of about 28,399 (260)
Regulatory myeloid cells paralyze T cells through cell–cell transfer of the metabolite methylglyoxal
Tobias Baumann +36 more
semanticscholar +1 more source
Cells Producing Their Own Nemesis: Understanding Methylglyoxal Metabolism
Methylglyoxal, which is technically known as 2-oxopropanal or pyruvaldehyde, shows typical reactions of carbonyl compounds as it has both an aldehyde and a ketone functional group. It is an extremely cytotoxic physiological metabolite, which is generated
Chakravortty, Dipshikha +5 more
core +1 more source
Methylglyoxal Effects on Cell Division of Scenedesmus quadricauda (Scenedesmaceae)
Cell division of ggeneflesmus quadricauda (Turp.) Breb. (Scenedesmaceae) is enhanced by methylglyoxal, a general inhibitor of cell division, at threshold concentration in conjunction with treatment timing related to growth stage of batch cultures. At 0.5
Rhie, Kitae
core
The nonenzymatic glycation process initiates a harmful cycle that generates various intermediate compounds, leading to carbonyl and oxidative stress, and ultimately resulting in the formation of advanced glycation end products (AGEs).
Saheem Ahmad +10 more
doaj +1 more source
Toxicity of methylglyoxal towards rat enterocytes and colonocytes
Effect of methylglyoxal, a bacterial metabolic product, on protein, DNA, and RNA synthesis in rat enterocytes and colonocytes was investigated. Results showed that 1 mM methylglyoxal inhibited protein, DNA, and RNA synthesis to the extent of 65-85, 65-80,
Baskaran, S., Balasubramanian, K. A.
core
Isolation and Characterization of Proteus vulgaris Methylglyoxal Synthetase [PDF]
Methylglyoxal synthetase, which catalyzes the formation of methylglyoxal and inorganic phosphate from dihydroxyacetone phosphate, was found in extracts of Proteus vulgaris.
Tsai, Pei-Kuo
core
Compounds Blocking Methylglyoxal-induced Protein Modification and Brain Endothelial Injury
BACKGROUND AND AIMS: Elevated levels of reactive carbonyl species such as methylglyoxal triggers carbonyl stress and activates a series of inflammatory responses leading to accelerated vascular damage.
Walter, Fruzsina +8 more
core +1 more source
Placental Methylglyoxal in Preeclampsia: Vascular and Biomarker Implications
BACKGROUND: Preeclampsia is a multifaceted syndrome that includes maternal vascular dysfunction. We hypothesize that increased placental glycolysis and hypoxia in preeclampsia lead to increased levels of methylglyoxal (MGO), consequently causing vascular dysfunction. METHODS:
Philippe Vangrieken +8 more
openaire +2 more sources
Methylglyoxal is a highly reactive ⍺-oxoaldehyde that arises as a by-product of glycolysis, lipid metabolism, and amino acid metabolism. Methylglyoxal reacts with protein, lipids, and DNA to form advanced glycation end-products (AGEs) that contribute to ...
Boggess, Ryan
core
Methylglyoxal 내성과 연관된 대장균 유전자의 탐색
학위논문(석사) - 한국과학기술원 : 생명과학과, 2006.2, [ 4, 35 p. ]Methylglyoxal (MG) acts as a toxic material in various species, known as a reactive α-oxoaldehyde having potential risk in disease. But it can be degraded by the in vivo biochemical pathway.
윤진영, Yoon, Jin-Young
core

