Results 131 to 140 of about 28,399 (260)

Regulatory myeloid cells paralyze T cells through cell–cell transfer of the metabolite methylglyoxal

open access: yesNature Immunology, 2020
Tobias Baumann   +36 more
semanticscholar   +1 more source

Cells Producing Their Own Nemesis: Understanding Methylglyoxal Metabolism

open access: yes, 2014
Methylglyoxal, which is technically known as 2-oxopropanal or pyruvaldehyde, shows typical reactions of carbonyl compounds as it has both an aldehyde and a ketone functional group. It is an extremely cytotoxic physiological metabolite, which is generated
Chakravortty, Dipshikha   +5 more
core   +1 more source

Methylglyoxal Effects on Cell Division of Scenedesmus quadricauda (Scenedesmaceae)

open access: yes, 1990
Cell division of ggeneflesmus quadricauda (Turp.) Breb. (Scenedesmaceae) is enhanced by methylglyoxal, a general inhibitor of cell division, at threshold concentration in conjunction with treatment timing related to growth stage of batch cultures. At 0.5
Rhie, Kitae
core  

Antiglycating activity of biomimetically synthesized magnetic copper ferrite nanoparticles: inhibition of methylglyoxal-derived AGEs

open access: yesFrontiers in Nanotechnology
The nonenzymatic glycation process initiates a harmful cycle that generates various intermediate compounds, leading to carbonyl and oxidative stress, and ultimately resulting in the formation of advanced glycation end products (AGEs).
Saheem Ahmad   +10 more
doaj   +1 more source

Toxicity of methylglyoxal towards rat enterocytes and colonocytes

open access: yes, 1990
Effect of methylglyoxal, a bacterial metabolic product, on protein, DNA, and RNA synthesis in rat enterocytes and colonocytes was investigated. Results showed that 1 mM methylglyoxal inhibited protein, DNA, and RNA synthesis to the extent of 65-85, 65-80,
Baskaran, S., Balasubramanian, K. A.
core  

Isolation and Characterization of Proteus vulgaris Methylglyoxal Synthetase [PDF]

open access: yes, 1975
Methylglyoxal synthetase, which catalyzes the formation of methylglyoxal and inorganic phosphate from dihydroxyacetone phosphate, was found in extracts of Proteus vulgaris.
Tsai, Pei-Kuo
core  

Compounds Blocking Methylglyoxal-induced Protein Modification and Brain Endothelial Injury

open access: yes, 2014
BACKGROUND AND AIMS: Elevated levels of reactive carbonyl species such as methylglyoxal triggers carbonyl stress and activates a series of inflammatory responses leading to accelerated vascular damage.
Walter, Fruzsina   +8 more
core   +1 more source

Placental Methylglyoxal in Preeclampsia: Vascular and Biomarker Implications

open access: yesHypertension
BACKGROUND: Preeclampsia is a multifaceted syndrome that includes maternal vascular dysfunction. We hypothesize that increased placental glycolysis and hypoxia in preeclampsia lead to increased levels of methylglyoxal (MGO), consequently causing vascular dysfunction. METHODS:
Philippe Vangrieken   +8 more
openaire   +2 more sources

Investigating Metformin as a Scavenger of Methylglyoxal to Impact Against Downstream Biological Effects

open access: yes, 2023
Methylglyoxal is a highly reactive ⍺-oxoaldehyde that arises as a by-product of glycolysis, lipid metabolism, and amino acid metabolism. Methylglyoxal reacts with protein, lipids, and DNA to form advanced glycation end-products (AGEs) that contribute to ...
Boggess, Ryan
core  

Methylglyoxal 내성과 연관된 대장균 유전자의 탐색

open access: yes, 2006
학위논문(석사) - 한국과학기술원 : 생명과학과, 2006.2, [ 4, 35 p. ]Methylglyoxal (MG) acts as a toxic material in various species, known as a reactive α-oxoaldehyde having potential risk in disease. But it can be degraded by the in vivo biochemical pathway.
윤진영, Yoon, Jin-Young
core  

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