Results 111 to 120 of about 16,994 (228)

Cytotoxic action of methylglyoxal on insulin-secreting cells

, 2001
Methylglyoxal is a spontaneous product of glucose metabolism which is known to have cytotoxic actions and to be present in raised concentrations in hyperglycaemia. It could therefore play an important role in glucose toxicity.
Elizabeth A. Sheader, Benson, Roderick S P, Sheader, Elizabeth A., Best, Leonard, Roderick S.P. Benson, Leonard Best   +5 more
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Cancerostatic Action of Methylglyoxal [PDF]

Science, 1968
L G, Együd, A, Szent-Györgyi
openaire   +2 more sources

Nanofabrication of methylglyoxal with chitosan biopolymer: a potential tool for enhancement of its anticancer effect

, 2015
Aparajita Pal,1,* Dipa Talukdar,1,* Anirban Roy,1 Subhankar Ray,2 Asish Mallick,3 Chitra Mandal,3 Manju Ray1 1Department of Biophysics, Bose Institute, Kolkata, India; 2Department of Biochemistry, University of Calcutta, Kolkata, India; 3Cancer Biology ...
Talukdar D, Mandal C, Mallick A, Ray M, Pal A, Roy A, Ray S   +6 more
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Utilization of Methylglyoxal in Animal Tissues

Experimental Biology and Medicine, 1957
SummaryMethylglyoxal has been incubated with rat liver extracts in the presence of kidney antiglyoxalase. During incubation, methylglyoxal and inorganic P decrease, whereas total hydrolyzable P increases. The hydrolysis curve of the Ba insoluble fraction of liver incubated with methylglyoxal resembles that obtained from hexose phosphate.
openaire   +2 more sources

Characterization of the Deoxyguanosine–Lysine Cross-Link of Methylglyoxal

, 2015
Methylglyoxal is a mutagenic bis-electrophile that is produced endogenously from carbohydrate precursors. Methylglyoxal has been reported to induce DNA–protein cross-links (DPCs) in vitro and in cultured cells.
Donald F. Stec (1265898), Carmelo J. Rizzo (1265235), Amy D. Millsap (1322637), Katya V. Petrova (1322634)   +3 more
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Methylglyoxal 내성과 연관된 대장균 유전자의 탐색

, 2006
학위논문(석사) - 한국과학기술원 : 생명과학과, 2006.2, [ 4, 35 p. ]Methylglyoxal (MG) acts as a toxic material in various species, known as a reactive α-oxoaldehyde having potential risk in disease. But it can be degraded by the in vivo biochemical pathway.
윤진영, Yoon, Jin-Young
core  

Antiglycating activity of biomimetically synthesized magnetic copper ferrite nanoparticles: inhibition of methylglyoxal-derived AGEs

Frontiers in Nanotechnology
The nonenzymatic glycation process initiates a harmful cycle that generates various intermediate compounds, leading to carbonyl and oxidative stress, and ultimately resulting in the formation of advanced glycation end products (AGEs).
Saheem Ahmad, Uzma Shahab, Jalaluddin M. Ashraf, Amjad R. Alyahyawi, Mohammad Azam Ansari, Sana Fatma, Ahmed Alshammari, Rihab Akasha, Sarah Asiri, Paridhi Puri, Afreen Khanam   +10 more
doaj   +1 more source

Placental Methylglyoxal in Preeclampsia: Vascular and Biomarker Implications

Hypertension
BACKGROUND: Preeclampsia is a multifaceted syndrome that includes maternal vascular dysfunction. We hypothesize that increased placental glycolysis and hypoxia in preeclampsia lead to increased levels of methylglyoxal (MGO), consequently causing vascular dysfunction. METHODS:
Philippe Vangrieken, Salwan Al-Nasiry, Alex H.V. Remels, Paul M.H. Schiffers, Emma Janssen, Stefanie Nass, Jean L.J.M. Scheijen, Marc E.A. Spaanderman, Casper G. Schalkwijk   +8 more
openaire   +2 more sources

Metabolism of Methylglyoxal by Scenedesmus Quadricauda [PDF]

, 1970
The purpose of this study was to investigate the metabolic pathways of methylglyoxal in S ...
Rounsavall, Terry Yale
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Toxicity of methylglyoxal towards rat enterocytes and colonocytes

, 1990
Effect of methylglyoxal, a bacterial metabolic product, on protein, DNA, and RNA synthesis in rat enterocytes and colonocytes was investigated. Results showed that 1 mM methylglyoxal inhibited protein, DNA, and RNA synthesis to the extent of 65-85, 65-80,
Baskaran, S., Balasubramanian, K. A.
core   +1 more source